The Laboratory RatMark A. Suckow, Steven H. Weisbroth, Craig L. Franklin Elsevier, 2005 M12 20 - 928 pages The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
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From inside the book
Results 6-10 of 81
Page 135
... occurs in mice during recovery from administered cytotoxics, it is less characteristic of the response in the rat and ... occur. Because immune-mediated destruction of red cells is highly regenerative, the RDW is generally increased. The ...
... occurs in mice during recovery from administered cytotoxics, it is less characteristic of the response in the rat and ... occur. Because immune-mediated destruction of red cells is highly regenerative, the RDW is generally increased. The ...
Page 136
... occurring and experimentally generated genetic mutants manifest a diverse array of hereditary anemias (Car and Eng ... occur as artifacts of drying blood smears, but may also be secondary to renal toxicity (Gojer, 1992). Acanthocytes ...
... occurring and experimentally generated genetic mutants manifest a diverse array of hereditary anemias (Car and Eng ... occur as artifacts of drying blood smears, but may also be secondary to renal toxicity (Gojer, 1992). Acanthocytes ...
Page 138
... occurs secondary to fluid loss or decreased fluid intake. Prerenal and renal azotemia sometimes coexist, confounding interpretation. Azotemia may also occur with increased protein catabolism or with gastrointestinal bleeding. BUN and ...
... occurs secondary to fluid loss or decreased fluid intake. Prerenal and renal azotemia sometimes coexist, confounding interpretation. Azotemia may also occur with increased protein catabolism or with gastrointestinal bleeding. BUN and ...
Page 139
... occur in rats given high doses of HMG CoA reductase inhibitors (e.g., cerivastatin), but this is a relatively unusual finding in toxicity studies or naturally occurring diseases of the rat. Following skeletal or cardiac muscle injury ...
... occur in rats given high doses of HMG CoA reductase inhibitors (e.g., cerivastatin), but this is a relatively unusual finding in toxicity studies or naturally occurring diseases of the rat. Following skeletal or cardiac muscle injury ...
Page 140
... occur secondary to high dose toxicities. Typically, assessments from which alterations in acid-base metabolism may be interpolated include changes in potassium (increased with metabolic acidosis), HCO3 À or total carbon dioxide (TCO2) ...
... occur secondary to high dose toxicities. Typically, assessments from which alterations in acid-base metabolism may be interpolated include changes in potassium (increased with metabolic acidosis), HCO3 À or total carbon dioxide (TCO2) ...
Contents
53 | |
71 | |
93 | |
127 | |
147 | |
165 | |
8 Analysis of Behavior in Laboratory Rats | 191 |
9 Nutrition | 219 |
18 Experimental Modeling and Research Methodology | 587 |
19 Anesthesia and Analgesia | 627 |
20 Euthanasia and Necropsy | 665 |
21 Integrating Biology with Rat Genomic Tools | 679 |
22 Gnotobiotics | 693 |
23 Spontaneous Surgically and Chemically Induced Models of Disease | 711 |
24 The Nude Rat | 733 |
25 Gerontology and AgeAssociated Lesions | 761 |
10 Housing and Environment | 303 |
11 Bacterial Mycoplasmal and Mycotic Infections | 339 |
12 Viral Disease | 423 |
13 Parasitic Diseases | 453 |
14 Neoplastic Disease | 479 |
15 Metabolic Traumatic and Miscellaneous Diseases | 513 |
16 Medical Management and Diagnostic Approaches | 547 |
17 Occupational Health and Safety | 565 |
26 Cardiovascular Research | 773 |
27 Toxicology | 803 |
28 Embryology and Teratology | 817 |
29 Immunology | 847 |
30 Wild and Black Rats | 865 |
Appendix 1 Selected Normative Data | 883 |
Index | 885 |
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