The Laboratory RatMark A. Suckow, Steven H. Weisbroth, Craig L. Franklin Elsevier, 2005 M12 20 - 928 pages The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
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From inside the book
Results 1-5 of 82
Page 25
... genes separable in crosses from the hooded gene, which had not itself been changed. The results were shown to be due to the operation of multiple modifying factors (Castle and Phillips, 1914; Dunn, 1967). Thus, a basic understanding of ...
... genes separable in crosses from the hooded gene, which had not itself been changed. The results were shown to be due to the operation of multiple modifying factors (Castle and Phillips, 1914; Dunn, 1967). Thus, a basic understanding of ...
Page 33
... gene pool has contributed far more strains of rats than any other single line. In fact, the contribution of the commercial Wistar colony to the total gene pool of all modern strains and stocks of rats may exceed the combined influence ...
... gene pool has contributed far more strains of rats than any other single line. In fact, the contribution of the commercial Wistar colony to the total gene pool of all modern strains and stocks of rats may exceed the combined influence ...
Page 77
... gene acts as an embryonic lethal, whereas in the heterozygous state it leads to renal cell carcinoma, uterine ... genes. As the genomes of inbred strains are highly standardized (F > 40), mutations can be identified and isolated much ...
... gene acts as an embryonic lethal, whereas in the heterozygous state it leads to renal cell carcinoma, uterine ... genes. As the genomes of inbred strains are highly standardized (F > 40), mutations can be identified and isolated much ...
Page 81
... gene, Hwy, located on RNO15. IER Ihara epileptic rat; strain with hereditary neuronal microdysgenesis and aquired lesions in the hippocampal formation leading to abnormal behavior, circling, various degrees of seizure activities, and ...
... gene, Hwy, located on RNO15. IER Ihara epileptic rat; strain with hereditary neuronal microdysgenesis and aquired lesions in the hippocampal formation leading to abnormal behavior, circling, various degrees of seizure activities, and ...
Page 83
... gene causing analbuminemia NBL black hooded Bogden in the mid-1970s from non-inbred Noble (Nb) rats. NBR black NIH black rats; Poiley at NIH from heterogeneous stock. NEDH albino Slonaker (Univ. of Chicago ca. 1928) rats inbred by ...
... gene causing analbuminemia NBL black hooded Bogden in the mid-1970s from non-inbred Noble (Nb) rats. NBR black NIH black rats; Poiley at NIH from heterogeneous stock. NEDH albino Slonaker (Univ. of Chicago ca. 1928) rats inbred by ...
Contents
53 | |
71 | |
93 | |
5Clinical Pathology of the Rat | 127 |
6 Reproduction and Breeding | 147 |
7 Assisted Reproductive Technologies and Genetic Modifications in Rats | 165 |
8 Analysis of Behavior in Laboratory Rats | 191 |
9 Nutrition | 219 |
18 Experimental Modeling and Research Methodology | 587 |
19 Anesthesia and Analgesia | 627 |
20 Euthanasia and Necropsy | 665 |
21 Integrating Biology with Rat Genomic Tools | 679 |
22 Gnotobiotics | 693 |
23 Spontaneous Surgically and Chemically Induced Models of Disease | 711 |
24 The Nude Rat | 733 |
25 Gerontology and AgeAssociated Lesions | 761 |
10 Housing and Environment | 303 |
11 Bacterial Mycoplasmal and Mycotic Infections | 339 |
12 Viral Disease | 423 |
13 Parasitic Diseases | 453 |
14 Neoplastic Disease | 479 |
15 Metabolic Traumatic and Miscellaneous Diseases | 513 |
16 Medical Management and Diagnostic Approaches | 547 |
17 Occupational Health and Safety | 565 |
26 Cardiovascular Research | 773 |
27 Toxicology | 803 |
28 Embryology and Teratology | 817 |
29 Immunology | 847 |
30 Wild and Black Rats | 865 |
Appendix 1 Selected Normative Data | 883 |
Index | 885 |
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Common terms and phrases
acid activity albino altered appear associated behavior Biol blood body bone brain breeding cage calcium cancer cause cells changes chemical clinical colony compared concentrations containing decreased deficiency detection determine diet dietary disease effects environment et al experimental factors female function gene genetic gland glucose growth Health host housed human immune important inbred incidence increased indicate induced infection influence Institute intestinal involved iron isolated Laboratory Animal laboratory rats lesions levels liver male metabolism methods mice mouse natural normal Nutr Nutrition observed occur organism Pneumocystis Press prevent production protein rats fed reduced reported reproductive respiratory response rodents role selected serum showed shown species spontaneous strains studies tion tissue treatment tumors University virus vitamin Wistar