The Laboratory RatMark A. Suckow, Steven H. Weisbroth, Craig L. Franklin Elsevier, 2005 M12 20 - 928 pages The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
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From inside the book
Results 1-5 of 82
Page 32
... determine whether there is an inheritance factor in susceptibility and resistance to dental caries in the albino rat. We therefore undertook to build a caries susceptible line, and a caries resistant line, using phenotypic selection ...
... determine whether there is an inheritance factor in susceptibility and resistance to dental caries in the albino rat. We therefore undertook to build a caries susceptible line, and a caries resistant line, using phenotypic selection ...
Page 54
... determine the minimal number of animals needed for a given experiment. The last phase sought to further reduce experimental variation by controlling the variance between individual animals (i.e., by increasing physiologic uniformity ...
... determine the minimal number of animals needed for a given experiment. The last phase sought to further reduce experimental variation by controlling the variance between individual animals (i.e., by increasing physiologic uniformity ...
Page 57
... determine environmental enrichment needs for all vertebrate animals (including laboratory rats) housed in their ... determined to be the choice that provides the animal with the greatest psychological benefit (PattersonKane et al., 2001b) ...
... determine environmental enrichment needs for all vertebrate animals (including laboratory rats) housed in their ... determined to be the choice that provides the animal with the greatest psychological benefit (PattersonKane et al., 2001b) ...
Page 61
... determined to be out of compliance with their approved Assurance, OLAW has the authority to disapprove, restrict, or ... determines that the incident has not been fully addressed at the level of the institution, several different actions ...
... determined to be out of compliance with their approved Assurance, OLAW has the authority to disapprove, restrict, or ... determines that the incident has not been fully addressed at the level of the institution, several different actions ...
Page 63
... determine if new areas of research could be supported that would address the legislative objectives. NIH support would be made available for applications that focused on the development of nonmammalian model systems and other ...
... determine if new areas of research could be supported that would address the legislative objectives. NIH support would be made available for applications that focused on the development of nonmammalian model systems and other ...
Contents
53 | |
71 | |
93 | |
127 | |
147 | |
165 | |
8 Analysis of Behavior in Laboratory Rats | 191 |
9 Nutrition | 219 |
18 Experimental Modeling and Research Methodology | 587 |
19 Anesthesia and Analgesia | 627 |
20 Euthanasia and Necropsy | 665 |
21 Integrating Biology with Rat Genomic Tools | 679 |
22 Gnotobiotics | 693 |
23 Spontaneous Surgically and Chemically Induced Models of Disease | 711 |
24 The Nude Rat | 733 |
25 Gerontology and AgeAssociated Lesions | 761 |
10 Housing and Environment | 303 |
11 Bacterial Mycoplasmal and Mycotic Infections | 339 |
12 Viral Disease | 423 |
13 Parasitic Diseases | 453 |
14 Neoplastic Disease | 479 |
15 Metabolic Traumatic and Miscellaneous Diseases | 513 |
16 Medical Management and Diagnostic Approaches | 547 |
17 Occupational Health and Safety | 565 |
26 Cardiovascular Research | 773 |
27 Toxicology | 803 |
28 Embryology and Teratology | 817 |
29 Immunology | 847 |
30 Wild and Black Rats | 865 |
Appendix 1 Selected Normative Data | 883 |
Index | 885 |
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Common terms and phrases
acid activity albino altered appear associated behavior Biol blood body bone brain breeding cage calcium cancer cause cells changes chemical clinical colony compared concentrations containing decreased deficiency detection determine diet dietary disease effects environment et al experimental factors female function gene genetic gland glucose growth Health host housed human immune important inbred incidence increased indicate induced infection influence Institute intestinal involved iron isolated Laboratory Animal laboratory rats lesions levels liver male metabolism methods mice mouse natural normal Nutr Nutrition observed occur organism Pneumocystis Press prevent production protein rats fed reduced reported reproductive respiratory response rodents role selected serum showed shown species spontaneous strains studies tion tissue treatment tumors University virus vitamin Wistar