Clinical Trials: Design, Conduct, and AnalysisOxford University Press, 1986 - 469 pages The definitive reference work on clinical trials, this book presents a wealth of detailed, practical information on the design, conduct, and analysis of both single center and multicenter trials. No other book on clinical trials offers as much detail as Meinert does on such issues as sample size calculation, stratification and randomization, data systems design, consent form development, publication policies, preparation of funding requests, and reporting procedures. |
From inside the book
Results 1-3 of 84
Page 91
... assignment probabilities for the treat- ments change as a function of the distribution of previous assignments , observed baseline charac- teristics , or observed outcomes . The emphasis in this chapter is on fixed ran- domization ...
... assignment probabilities for the treat- ments change as a function of the distribution of previous assignments , observed baseline charac- teristics , or observed outcomes . The emphasis in this chapter is on fixed ran- domization ...
Page 101
... assignment schedule is followed , as listed in Table 10-8 . The preferred system is one in which alloca- tions are ... assignment list • Copy of the assignment list B. For procedures using computer based pseudo - random number generators ...
... assignment schedule is followed , as listed in Table 10-8 . The preferred system is one in which alloca- tions are ... assignment list • Copy of the assignment list B. For procedures using computer based pseudo - random number generators ...
Page 199
... assignment once it has been revealed to the clinic ? Answer : No. The assignment and the pa- tient for whom it was intended should be counted in the study once it has been disclosed . Care should be taken to make certain that the ...
... assignment once it has been revealed to the clinic ? Answer : No. The assignment and the pa- tient for whom it was intended should be counted in the study once it has been disclosed . Care should be taken to make certain that the ...
Contents
CURRENT STATUS | 1 |
Table 21 Number of trials median | 11 |
2235 | 14 |
Copyright | |
16 other sections not shown
Other editions - View all
Clinical Trials: Design, Conduct, and Analysis Curtis L. Meinert,Susan Tonascia Limited preview - 1986 |
Common terms and phrases
allocation ratio allocation schedule Aspirin assess baseline block block size Chapter clinic personnel clinical trials close-out codes committee comparisons consent control treatment Coronary Drug Project cost data center data collection data dredging data entry data forms disease dropouts Drug Project Research edit error Fisher's exact test follow-up visits funding Gallstone Glossary Group Diabetes Program Hypertension hypoglycemic identify indicate initial Institute investigators laboratory masked ment methods multicenter trials Myocardial Infarction needed niacin number of patients outcome measure p-value patient recruitment patients enrolled phenformin physician placebo procedures Program Research Group Project Research Group protocol Question random numbers records responsible sample size Section single-center specified sponsor stratification study treatments Table test treatment tients tion tolbutamide treat treatment allocation treatment assignment treatment effects treatment groups trials involving trials sketched UGDP University Group Diabetes variables