Congenital and Perinatal Infections

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Cecelia Hutto, Gwendolyn B. Scott
Springer Science & Business Media, 2007 M10 28 - 314 pages
A concise clinical reference that facilitates the diagnosis of intrauterine and perinatally acquired infections was the goal in creating the Congenital and Perinatal Infections: A Concise Guide to Diagnosis. Information about the natural history, m- agement, and outcome of these infections is well detailed in many other sources and so has not been included. Rather, the focus of the book is diagnosis. The initial chapters provide general information about serological and nonserological assays that are used for the diagnosis of infections, and a chapter about the placenta includes details about histopathological findings that can be helpful with the diagnosis of congenital inf- tions. The remainder of the book is devoted to the diagnosis of specific congenital and/ or perinatal infections. As illustrated in the chapters about specific infections, the approach to diagnosis of a congenital or perinatally acquired infection in the neonate begins, when possible, with consideration and diagnosis of infection in the pregnant woman, knowledge of how the infection is transmitted, and the risk of that infection for the woman and her fetus or neonate. The possibility of congenital or perinatal infection in neonates is usually considered because of the diagnosis of, or concern about a s- cific infection in, a mother during pregnancy that can be transmitted to the neonate or because of clinical findings in the neonate at birth that suggest an infectious cause.

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Contents

Serology
7
Nonserologic Assays for Detection of Bacteria
13
Diagnosis of Viral Infections by Viral Isolation and Identification
23
Placental Histopathology
37
Herpes Simplex Virus
63
Cytomegalovirus
73
EpsteinBarr Virus
87
Charles T Leach
101
Human Immunodeficiency Virus Type 1
157
Lymphocytic Choriomeningitis Virus
181
Syphilis
199
Group B Streptococcus
217
Kim Connelly Smith and Jeffrey R Starke
233
23
261
63
281
Candida
289

Human Herpesvirus 8
111
Rubella
123
Parvovirus
131
13
143
Index
309
73
310
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