...proof of effectiveness.121 A federal committee investigating gene therapy cautioned: "Over, selling of the results of laboratory and clinical studies...further developed and more successful than it actually is."122 Even the educational materials provided to individual patients in connection with a particular...

...humans found that this was not the case.83 A federal committee investigating gene therapy cautioned, "Overselling of the results of laboratory and clinical...further developed and more successful than it actually is."84 In fact, the one study that seemed to indicate a clear benefit of somatic cell gene therapy...

...of the RAC's approval of Wilson's OTC protocol. Its authors, Stuart Orkin and Arno Motulsky, wrote that "overselling of the results of laboratory and...clinical studies by investigators and their sponsors . . . has lead to the mistaken and widespread perception that gene therapy is further developed and...

...of the results of laboratory and clinical studies by investigators and their sponsors ... has lead to the mistaken and widespread perception that gene...developed and more successful than it actually is." Orkin and Motulsky pointed to unsolved problems in all aspects of the field, including "shortcomings...

...fundamental disease pathophysiology. In one particularly critical finding, the panel's report stated: "Overselling of the results of laboratory and clinical...successful application of gene therapy to human disease." The panel had strong recommendations, including that the investigators and sponsors should "be more...