The Dog and Its GenomeElaine A. Ostrander, Urs Giger, Kerstin Lindblad-Toh Cold Spring Harbor Laboratory Press, 2006 - 584 pages Dogs of different breeds can range remarkably in size, shape, and behavior, and yet they all carry essentially the same genome, making them a particularly fascinating model for genome plasticity. The recent release of the complete sequence of the dog genome provides an exciting new context in which to consider such variation. Twenty–five chapters written by experts in the field include various aspects of morphological and behavioral variation in dogs, their origins and domestication, and their unique value as a model system for many common but complex human diseases such as diabetes and cancer. |
Contents
BREED CLUBS AND CANINE HISTORY | 1 |
The Kennel Club and the Early History of Dog Shows | 19 |
American Breed Clubs and Health Initiatives | 31 |
Copyright | |
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Acland G.M. affected dogs Aguirre G.D. alleles American Kennel Club amino acid analysis animals associated autosomal backcross Bedlington terriers behavior boxer Breen cancer candidate gene canine canine genome Canis familiaris cDNA cell chromosome clade clinical clones collie copper toxicosis cystine cystinuria cytogenetic detection dilated cardiomyopathy disease disorders dog breeds dog genome dog population domestic dog exon F₁ factor genetic genome sequence genotypes German shepherd German shepherd dogs Giger golden retriever gonadal haplotypes hemophilia heritability hip dysplasia human hybrid identified inherited karyotype Kennel Club Labrador retriever loci locus lymphoma mapping markers microsatellite molecular morphological mouse mtDNA mtDNA types MURR1 mutation Natl normal origin Ostrander E.A. Patterson D.F. pedigree phenotype polymorphism Portuguese water dog progressive retinal atrophy protein receptor region retinal Savolainen selection setters SNPs species studies tumors variation Veterinary Vilà wolf wolves X-linked