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Page 63
During the first and also the second weeks , acinar cells start to bud off from the tubules , forming crescents around these terminal tubules . Large numbers of acini and terminal tubules with crescents and buds are seen during the ...
During the first and also the second weeks , acinar cells start to bud off from the tubules , forming crescents around these terminal tubules . Large numbers of acini and terminal tubules with crescents and buds are seen during the ...
Page 110
... and Drug Administration Guidelines for Animal Toxicity Studies Requirements for subacute or chronic toxicity studies Category Duration of human administration Study phase Oral or parenteral Several days As long as 2 weeks As long as ...
... and Drug Administration Guidelines for Animal Toxicity Studies Requirements for subacute or chronic toxicity studies Category Duration of human administration Study phase Oral or parenteral Several days As long as 2 weeks As long as ...
Page 131
tered intravenously with 103 cells , resulting in a mean survival rats fed 0.2 % had progressive lesions beginning with mild time of 14 to 21 days ( 31 ) . hyperplasia at 2 to 4 weeks , to moderate hyperplasia at 6 to 8 The Murphy ...
tered intravenously with 103 cells , resulting in a mean survival rats fed 0.2 % had progressive lesions beginning with mild time of 14 to 21 days ( 31 ) . hyperplasia at 2 to 4 weeks , to moderate hyperplasia at 6 to 8 The Murphy ...
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Contents
Substance Administration | 19 |
2 | 43 |
Contents of Volume I | 52 |
Copyright | |
14 other sections not shown
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Common terms and phrases
Acad activity addition adult agents antibody antigens appear Arch Biol blood body cages Cancer Cancer Res carcinogenesis carcinogens carcinomas cells changes chemical collection compared compounds continued described determine diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland groups growth heart host human immune Immunol inbred incidence increased induced infection isolated Laboratory Animals laboratory rat lesions liver lymphocytes major male material method mg/kg mice months mouse natural normal observed obtained occur oral organ Pathology period placenta potential present Press Proc procedure produced Reference reported response selected skin species spontaneous strain studies surface Table technique teratogenic tion tissue toxicity transplantable tumors various weeks weight Wistar York
Bibliographic information
| Title | The Laboratory Rat: Research applications Volume 2 of American College of Laboratory Animal Medicine series, American College of Laboratory Animal Medicine Volume 2 of The Laboratory Rat, Steven H. Weisbroth The Laboratory Rat: Research Applications V. II, James Russell Lindsey |
| Editors | Henry J. Baker, James Russell Lindsey, Steven H. Weisbroth |
| Edition | illustrated |
| Publisher | Academic Press, 1980 |
| Original from | the University of Michigan |
| Digitized | 26 Feb 2010 |
| ISBN | 0120749025, 9780120749027 |
| Length | 276 pages |
| Export Citation | BiBTeX EndNote RefMan |