The Laboratory Rat: Research applicationsHenry J. Baker, James Russell Lindsey, Steven H. Weisbroth Academic Press, 1980 - 276 pages |
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Page 105
... studies involving drug distribution within the body and mechanisms of drug action and toxicity . Laboratory rats are commonly used as the rodent species of choice , along with the mongrel or Beagle dog as the nonrodent species , to ...
... studies involving drug distribution within the body and mechanisms of drug action and toxicity . Laboratory rats are commonly used as the rodent species of choice , along with the mongrel or Beagle dog as the nonrodent species , to ...
Page 109
... studies ( phase I ) Study - rats Reproduction and fertility ) Segment II teratology study Mechanism of action Studies in man Fig . 1. Key research and development activities in the pharmacologic and toxicologic testing of a typical new ...
... studies ( phase I ) Study - rats Reproduction and fertility ) Segment II teratology study Mechanism of action Studies in man Fig . 1. Key research and development activities in the pharmacologic and toxicologic testing of a typical new ...
Page 111
... studies in experimental animals . In some in- stances , studies involving several generations are necessary to provide information on potentially long - term effects in hu- mans . Data from these studies also provide useful insight into ...
... studies in experimental animals . In some in- stances , studies involving several generations are necessary to provide information on potentially long - term effects in hu- mans . Data from these studies also provide useful insight into ...
Contents
Identification Methods | 4 |
Substance Administration | 19 |
Contents of Volume I | 38 |
Copyright | |
11 other sections not shown
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Academic Press adult agents albino rat Anat anesthesia anesthetic animal model antibody antigens Arch artery biochemical Biol blastocyst blood pressure BN/Bi body weight cage Cancer Cancer Res cannulation carcinogenesis carcinogens carcinomas cardiac caries cavity cells chemical chronic Clin dental dental caries diet disease dose drug duct effect embryo enzymes Ethylenethiourea evaluation experimental factors female flora genetic germfree germfree rats GF rats gland gnotobiotic growth human hypertension hypertrophy immune implantation inbred induced infection isolator laboratory animals laboratory rat lesions liver Long-Evans lymph lymphocytes male malformations metabolism method mice molars mouse myocardium myocytes N. Y. Acad Natl neoplasms normal oral organ Pathol Pathology Physiol placenta Proc procedure protein rodents salivary specific spontaneous Sprague-Dawley studies technique teratogenic Teratology thoracic duct tion tissue toxicity transplantable trophoblast trypan blue tumors ventricle vitamin vitro WAG/Rij Wistar Wistar rats yolk sac