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Page 105
Usually more than one species is selected when Screening tests using healthy rats evaluating a specific chemical because there may be many Central nervous system screening Maze studies similarities and some differences in toxic ...
Usually more than one species is selected when Screening tests using healthy rats evaluating a specific chemical because there may be many Central nervous system screening Maze studies similarities and some differences in toxic ...
Page 110
... II III NDA 2 Species , 2 weeks 2 Species , 2 weeks 2 Species , as long as 4 weeks 2 Species , as long as 3 months 2 ... 3 months 2 Species , 6 months or longer 2 Species , 12 months ( nonrodent ) , 18 months ( rodent ) 4 Species , 5 ...
... II III NDA 2 Species , 2 weeks 2 Species , 2 weeks 2 Species , as long as 4 weeks 2 Species , as long as 3 months 2 ... 3 months 2 Species , 6 months or longer 2 Species , 12 months ( nonrodent ) , 18 months ( rodent ) 4 Species , 5 ...
Page 239
All However , there are two rat - adapted malarias ( originally iso- three infections are spread by various species of the dipteran lated from wild African rodent species ) which have been used vector , Glossina ( tsetse fly ) ...
All However , there are two rat - adapted malarias ( originally iso- three infections are spread by various species of the dipteran lated from wild African rodent species ) which have been used vector , Glossina ( tsetse fly ) ...
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Contents
Substance Administration | 19 |
2 | 43 |
Contents of Volume I | 52 |
Copyright | |
14 other sections not shown
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Acad activity addition adult agents antibody antigens appear Arch Biol blood body cages Cancer Cancer Res carcinogenesis carcinogens carcinomas cells changes chemical collection compared compounds continued described determine diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland groups growth heart host human immune Immunol inbred incidence increased induced infection isolated Laboratory Animals laboratory rat lesions liver lymphocytes major male material method mg/kg mice months mouse natural normal observed obtained occur oral organ Pathology period placenta potential present Press Proc procedure produced Reference reported response selected skin species spontaneous strain studies surface Table technique teratogenic tion tissue toxicity transplantable tumors various weeks weight Wistar York