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Page 104
GENERAL CONSIDERATIONS IN SELECTING ANIMALS FOR TOXICOLOGICAL RESEARCH The biological effects of chemicals are determined by the dose of the chemical applied ( 9 ) . It is the responsibility of the Species selection of test animals in ...
GENERAL CONSIDERATIONS IN SELECTING ANIMALS FOR TOXICOLOGICAL RESEARCH The biological effects of chemicals are determined by the dose of the chemical applied ( 9 ) . It is the responsibility of the Species selection of test animals in ...
Page 105
A variety of factors influence the proper selection of the Test performed or system tested Recommended procedure animal model . Usually more than one species is selected when Screening tests using healthy rats evaluating a specific ...
A variety of factors influence the proper selection of the Test performed or system tested Recommended procedure animal model . Usually more than one species is selected when Screening tests using healthy rats evaluating a specific ...
Page 124
... at very low levels of exposure ( 258 ) , it is not recomication also must be considered in selecting the route of admin- mended as a routine procedure to replace conventional testing istration ( 125,363 ) . in young adults ( 303 ) .
... at very low levels of exposure ( 258 ) , it is not recomication also must be considered in selecting the route of admin- mended as a routine procedure to replace conventional testing istration ( 125,363 ) . in young adults ( 303 ) .
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Contents
Substance Administration | 19 |
2 | 43 |
Contents of Volume I | 52 |
Copyright | |
14 other sections not shown
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Common terms and phrases
Acad activity addition adult agents antibody antigens appear Arch Biol blood body cages Cancer Cancer Res carcinogenesis carcinogens carcinomas cells changes chemical collection compared compounds continued described determine diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland groups growth heart host human immune Immunol inbred incidence increased induced infection isolated Laboratory Animals laboratory rat lesions liver lymphocytes major male material method mg/kg mice months mouse natural normal observed obtained occur oral organ Pathology period placenta potential present Press Proc procedure produced Reference reported response selected skin species spontaneous strain studies surface Table technique teratogenic tion tissue toxicity transplantable tumors various weeks weight Wistar York
Bibliographic information
| Title | The Laboratory Rat: Research applications Volume 2 of American College of Laboratory Animal Medicine series, American College of Laboratory Animal Medicine Volume 2 of The Laboratory Rat, Steven H. Weisbroth The Laboratory Rat: Research Applications V. II, James Russell Lindsey |
| Editors | Henry J. Baker, James Russell Lindsey, Steven H. Weisbroth |
| Edition | illustrated |
| Publisher | Academic Press, 1980 |
| Original from | the University of Michigan |
| Digitized | 26 Feb 2010 |
| ISBN | 0120749025, 9780120749027 |
| Length | 276 pages |
| Export Citation | BiBTeX EndNote RefMan |