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Page 109
Production of a sample of test material to be used for normal and diseased human patients to determine the efficacy animal and clinical research studies . of the new drug . All data is scientifically evaluated and submit3.
Production of a sample of test material to be used for normal and diseased human patients to determine the efficacy animal and clinical research studies . of the new drug . All data is scientifically evaluated and submit3.
Page 132
Lesions in rats inocuproduced by essentially inert , insoluble materials such as glass , lated at 4 days of age were ... the same material was implanted in powdered , of polyoma virus ( 170 ) . finely shredded , or perforated forms .
Lesions in rats inocuproduced by essentially inert , insoluble materials such as glass , lated at 4 days of age were ... the same material was implanted in powdered , of polyoma virus ( 170 ) . finely shredded , or perforated forms .
Page 171
There are diffuse expansions of dense Z band material ( arrow ) . Scale , 1 um . Inset shows higher magnification of expanded Z band material ( Z ' ) present in SHR with cardiac hypertrophy . Scale , 1 um . ( From Kawamura et al .
There are diffuse expansions of dense Z band material ( arrow ) . Scale , 1 um . Inset shows higher magnification of expanded Z band material ( Z ' ) present in SHR with cardiac hypertrophy . Scale , 1 um . ( From Kawamura et al .
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Contents
Substance Administration | 19 |
2 | 43 |
Contents of Volume I | 52 |
Copyright | |
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Acad activity addition adult agents antibody antigens appear Arch Biol blood body cages Cancer Cancer Res carcinogenesis carcinogens carcinomas cells changes chemical collection compared compounds continued described determine diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland groups growth heart host human immune Immunol inbred incidence increased induced infection isolated Laboratory Animals laboratory rat lesions liver lymphocytes major male material method mg/kg mice months mouse natural normal observed obtained occur oral organ Pathology period placenta potential present Press Proc procedure produced Reference reported response selected skin species spontaneous strain studies surface Table technique teratogenic tion tissue toxicity transplantable tumors various weeks weight Wistar York