The Laboratory Rat: Research applicationsHenry J. Baker, James Russell Lindsey, Steven H. Weisbroth Academic Press, 1980 - 276 pages |
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Page 109
... drug . Table II Food and Drug Administration Guidelines for Animal Toxicity. more than 10 million dollars to develop a single new drug . As an average , more than 5000 chemicals are synthesized and investigated in order to finally ...
... drug . Table II Food and Drug Administration Guidelines for Animal Toxicity. more than 10 million dollars to develop a single new drug . As an average , more than 5000 chemicals are synthesized and investigated in order to finally ...
Page 115
... drug when administered over an extended period of time compatible with that for which the drug might be used when commercially available . These tests are specifically re- quired for drugs which will be given to human patients for long ...
... drug when administered over an extended period of time compatible with that for which the drug might be used when commercially available . These tests are specifically re- quired for drugs which will be given to human patients for long ...
Page 118
... drugs from the gastrointestinal tract . In " The Physiological Equivalence of Drug Dosing Forms , " Food and Drug Directorate , Ottawa , Canada . 7. Brodie , B. B. , and Reid , W. D. ( 1969 ) . Is man a unique animal in response to drugs ...
... drugs from the gastrointestinal tract . In " The Physiological Equivalence of Drug Dosing Forms , " Food and Drug Directorate , Ottawa , Canada . 7. Brodie , B. B. , and Reid , W. D. ( 1969 ) . Is man a unique animal in response to drugs ...
Contents
Identification Methods | 4 |
Substance Administration | 19 |
Contents of Volume I | 38 |
Copyright | |
11 other sections not shown
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Academic Press adult agents albino rat Anat anesthesia anesthetic animal model antibody antigens Arch artery biochemical Biol blastocyst blood pressure BN/Bi body weight cage Cancer Cancer Res cannulation carcinogenesis carcinogens carcinomas cardiac caries cavity cells chemical chronic Clin dental dental caries diet disease dose drug duct effect embryo enzymes Ethylenethiourea evaluation experimental factors female flora genetic germfree germfree rats GF rats gland gnotobiotic growth human hypertension hypertrophy immune implantation inbred induced infection isolator laboratory animals laboratory rat lesions liver Long-Evans lymph lymphocytes male malformations metabolism method mice molars mouse myocardium myocytes N. Y. Acad Natl neoplasms normal oral organ Pathol Pathology Physiol placenta Proc procedure protein rodents salivary specific spontaneous Sprague-Dawley studies technique teratogenic Teratology thoracic duct tion tissue toxicity transplantable trophoblast trypan blue tumors ventricle vitamin vitro WAG/Rij Wistar Wistar rats yolk sac