High Throughput Screening: The Discovery of Bioactive SubstancesCRC Press, 1997 M05 6 - 704 pages Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high |
From inside the book
Results 1-5 of 68
Page vii
... substances IX . Test sample preparations in microplate format X. Follow - up and recollection XI . Chemotaxonomy and phytochemical tracking XII . Conclusions 49 3 . Enzymes and Microbes as a Source of Chemical vii Contents.
... substances IX . Test sample preparations in microplate format X. Follow - up and recollection XI . Chemotaxonomy and phytochemical tracking XII . Conclusions 49 3 . Enzymes and Microbes as a Source of Chemical vii Contents.
Page 18
... microplates in 1993 , MicroSource has evolved into a provider of compounds individually for its microplate customers and as a service group for the management and plating of compound collections for both brokers and discovery based ...
... microplates in 1993 , MicroSource has evolved into a provider of compounds individually for its microplate customers and as a service group for the management and plating of compound collections for both brokers and discovery based ...
Page 19
... microplate . Modifications in extraction protocols , custom plate formatting , and custom collections of particular taxons or isolations from specific environments are also available . Pricing is based on size of order and payment ...
... microplate . Modifications in extraction protocols , custom plate formatting , and custom collections of particular taxons or isolations from specific environments are also available . Pricing is based on size of order and payment ...
Page 21
... microplates . WPBM also offers organism recollection as a bridge to scale - up development . Extracts are offered for non - exclusive outright sale . Microplates contain pre - weighed extracts at 20 μg , 100 ug or 2 mg per well ; costs ...
... microplates . WPBM also offers organism recollection as a bridge to scale - up development . Extracts are offered for non - exclusive outright sale . Microplates contain pre - weighed extracts at 20 μg , 100 ug or 2 mg per well ; costs ...
Page 60
You have reached your viewing limit for this book.
You have reached your viewing limit for this book.
Contents
Chemically Generated Screening Libraries | 145 |
Ill Assay Technologies and Detection Methods | 273 |
IV Automation and Robotics | 455 |
V Data Retrieval Handling and Integration | 547 |
VI Laboratory Design and Management | 623 |
Index | 669 |
Other editions - View all
High Throughput Screening: The Discovery of Bioactive Substances John P. Devlin Limited preview - 1997 |
Common terms and phrases
acid actinomycetes activity analysis antibody applications approach assay assay plate bar-code BIAcore binding assay biochemical biological diversity cells chelates Chem chemical diversity collection combinatorial chemistry combinatorial libraries companies components compounds concentration Contracting Party Convention cryptate database detection DMSO drug discovery enzyme evaluated example extracts Figure FlashPlate fluorescence format function gene handling high throughput screening HTRF HTS program identified immunoassays implementation incubation inhibition inhibitors instruments integrated interface labeled laboratory large numbers ligand luciferase marine natural products methods microbial microorganisms microplate molecular molecules neurotrophin operation optimization Oracle peptide performed pharmaceutical polyphenols protein protocol radioligand reaction reagents receptor reporter gene resin robotic system samples scintillation screening data screening program secondary metabolites signal solid phase solution specific streptavidin structure substrate synthesis synthetic Table target trkB workstations