High Throughput Screening: The Discovery of Bioactive SubstancesCRC Press, 1997 M05 6 - 704 pages Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high |
From inside the book
Results 1-5 of 77
Page x
... methods to reduce compromises in screening II . The diversity of HTS methods III . The future of HTS 15. Bioassay Design and Implementation ... Robert W. Wallace and Mark E. Goldman I. Introduction II . Target selection III . Types and ...
... methods to reduce compromises in screening II . The diversity of HTS methods III . The future of HTS 15. Bioassay Design and Implementation ... Robert W. Wallace and Mark E. Goldman I. Introduction II . Target selection III . Types and ...
Page xi
... Method for Drug Discovery . Alfred J. Kolb , Jocelyn W. Burke , and Gerard Mathis I. Introduction II . The theory of ... methods III . Results and discussion 22 . IV . Summary of advantages Fluorescence Polarization ....... J. Richard ...
... Method for Drug Discovery . Alfred J. Kolb , Jocelyn W. Burke , and Gerard Mathis I. Introduction II . The theory of ... methods III . Results and discussion 22 . IV . Summary of advantages Fluorescence Polarization ....... J. Richard ...
Page 7
... methods . Budgets for such programs often reach into the millions ( e.g. , the Merck / InBio , Pfizer / New York Botanical Garden collaborations ) and require a commitment to staff and facility support over years . Nevertheless , the ...
... methods . Budgets for such programs often reach into the millions ( e.g. , the Merck / InBio , Pfizer / New York Botanical Garden collaborations ) and require a commitment to staff and facility support over years . Nevertheless , the ...
Page 27
... methods for sustainable use of biological resources . Article 11. Incentive Measures Each Contracting Party shall , as far as possible and as appropriate , adopt economically and socially sound measures that act as incentives for the ...
... methods for sustainable use of biological resources . Article 11. Incentive Measures Each Contracting Party shall , as far as possible and as appropriate , adopt economically and socially sound measures that act as incentives for the ...
Page 90
You have reached your viewing limit for this book.
You have reached your viewing limit for this book.
Contents
Chemically Generated Screening Libraries | 145 |
Ill Assay Technologies and Detection Methods | 273 |
IV Automation and Robotics | 455 |
V Data Retrieval Handling and Integration | 547 |
VI Laboratory Design and Management | 623 |
Index | 669 |
Other editions - View all
High Throughput Screening: The Discovery of Bioactive Substances John P. Devlin Limited preview - 1997 |
Common terms and phrases
acid actinomycetes activity analysis antibody applications approach assay assay plate bar-code BIAcore binding assay biochemical biological diversity cells chelates Chem chemical diversity collection combinatorial chemistry combinatorial libraries companies components compounds concentration Contracting Party Convention cryptate database detection DMSO drug discovery enzyme evaluated example extracts Figure FlashPlate fluorescence format function gene handling high throughput screening HTRF HTS program identified immunoassays implementation incubation inhibition inhibitors instruments integrated interface labeled laboratory large numbers ligand luciferase marine natural products methods microbial microorganisms microplate molecular molecules neurotrophin operation optimization Oracle peptide performed pharmaceutical polyphenols protein protocol radioligand reaction reagents receptor reporter gene resin robotic system samples scintillation screening data screening program secondary metabolites signal solid phase solution specific streptavidin structure substrate synthesis synthetic Table target trkB workstations