High Throughput Screening: The Discovery of Bioactive SubstancesCRC Press, 1997 M05 6 - 704 pages Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high |
From inside the book
Results 1-5 of 72
Page xviii
... Instrument Company , 800 Research Parkway , Meriden , Connecticut , 06450 , U.S.A. Margaret Cain , NEN Life Sciences / E . I. du Pont de Nemours & Company , 549 Albany Street , Boston , Massachusetts , 02118 , U.S.A. Jorge Carmona ...
... Instrument Company , 800 Research Parkway , Meriden , Connecticut , 06450 , U.S.A. Margaret Cain , NEN Life Sciences / E . I. du Pont de Nemours & Company , 549 Albany Street , Boston , Massachusetts , 02118 , U.S.A. Jorge Carmona ...
Page xx
... Instrument Company , 800 Research Parkway , Meriden , Connecticut , 06450 , U.S.A. Janet M. Kolb , Department of Natural Products Research , Bristol - Myers Squibb Pharmaceutical Research Institute , Wallingford , Connecticut , 06492 ...
... Instrument Company , 800 Research Parkway , Meriden , Connecticut , 06450 , U.S.A. Janet M. Kolb , Department of Natural Products Research , Bristol - Myers Squibb Pharmaceutical Research Institute , Wallingford , Connecticut , 06492 ...
Page 10
... instrument parts and assay reagents are inaccessible , it is impossible to maintain . The preferred approach is to expand the skills already present in the developing country and absent in the developed partner . In a plant collection ...
... instrument parts and assay reagents are inaccessible , it is impossible to maintain . The preferred approach is to expand the skills already present in the developing country and absent in the developed partner . In a plant collection ...
Page 35
... instrument in question by the secretariat at least six months before the meeting at which it is proposed for adoption ... instruments of ratification , acceptance or approval by at least two thirds of the Contracting Parties to this ...
... instrument in question by the secretariat at least six months before the meeting at which it is proposed for adoption ... instruments of ratification , acceptance or approval by at least two thirds of the Contracting Parties to this ...
Page 36
... Instruments of ratification , acceptance or approval shall be deposited with the Depositary . 2. Any organization referred to in paragraph 1 above which becomes a Contracting Party to this Convention or any protocol without any of its ...
... Instruments of ratification , acceptance or approval shall be deposited with the Depositary . 2. Any organization referred to in paragraph 1 above which becomes a Contracting Party to this Convention or any protocol without any of its ...
Contents
Chemically Generated Screening Libraries | 145 |
Ill Assay Technologies and Detection Methods | 273 |
IV Automation and Robotics | 455 |
V Data Retrieval Handling and Integration | 547 |
VI Laboratory Design and Management | 623 |
Index | 669 |
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High Throughput Screening: The Discovery of Bioactive Substances John P. Devlin Limited preview - 1997 |
Common terms and phrases
acid actinomycetes activity analysis antibody applications approach assay assay plate bar-code BIAcore binding assay biochemical biological diversity cells chelates Chem chemical diversity collection combinatorial chemistry combinatorial libraries companies components compounds concentration Contracting Party Convention cryptate database detection DMSO drug discovery enzyme evaluated example extracts Figure FlashPlate fluorescence format function gene handling high throughput screening HTRF HTS program identified immunoassays implementation incubation inhibition inhibitors instruments integrated interface labeled laboratory large numbers ligand luciferase marine natural products methods microbial microorganisms microplate molecular molecules neurotrophin operation optimization Oracle peptide performed pharmaceutical polyphenols protein protocol radioligand reaction reagents receptor reporter gene resin robotic system samples scintillation screening data screening program secondary metabolites signal solid phase solution specific streptavidin structure substrate synthesis synthetic Table target trkB workstations