Retinoids and Carotenoids in DermatologyAnders Vahlquist, Madeleine Duvic CRC Press, 2007 M06 20 - 384 pages This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of |
Contents
| 1 | |
Implications for Epidermal Homeostasis Skin Barrier Function Wound Healing and Atopic Dermatitis | 27 |
From Vitamin A in Human Epidermis to the Pharmacology of Oral Retinoids in Dermatology | 55 |
Chapter 4 Recent Studies on the Pharmacokinetics and Metabolism of Retinoids in the Skin | 69 |
Chapter 5 Antiaging Effects of Retinoids and Mechanisms of Action | 77 |
Chapter 6 Retinoid Therapy of Acne and SebocyteRelated Disorders | 103 |
Chapter 7 Retinoids and Retinoic Acid Metabolism Blocking Agents in Psoriasis | 125 |
Chapter 8 Retinoid Treatment of the Disorders of Cornification | 153 |
Chapter 12 Retinoids in the Prevention and Treatment of Skin Cancer | 203 |
Chapter 13 Side Effects and Pitfalls in Retinoid Therapy | 225 |
Chapter 14 RetinoidInduced Hyperlipidemia and the Risk of Atherosclerosis | 249 |
An Overview | 261 |
Chapter 16 Antioxidative Effects of Carotenoids | 271 |
Chapter 17 BetaCarotene in the Treatment of Skin Disorders | 291 |
Chapter 18 Carotenoids as Cancer Preventive Agents | 307 |
Chapter 19 BetaCarotene in Erythropoietic Protoporphyria | 333 |
Chapter 9 Oral Retinoid Therapy in Children and Infants | 171 |
Chapter 10 Retinoids in Cutaneous TCell Lymphomas | 183 |
Chapter 11 Retinoid Therapy and Autoimmune Skin Disease | 197 |
Index | 345 |
Back cover | 369 |
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Common terms and phrases
acitretin acne action activity aging all-trans antioxidant appears application associated beta-carotene bexarotene binding Biol cancer carotenoids caused cells cellular changes Chem Clin clinical combination compared concentrations cream cutaneous damage decreased demonstrated Dermatology disease disorders dose drug efficacy enzymes epidermis esters et al etretinate exposure expression factor function gene growth half-life human skin hypothyroidism improvement increased induced inhibition Invest involved isotretinoin JAm Acad Dermatol keratinocytes lesions levels lichen planus ligand lipid lycopene mechanism metabolism mice mouse mutations natural normal observed occurs oral oxidative patients plasma potential prevention production protection protein psoriasis recently receptor reduced regulation reported response retinoic acid retinoids risk role severe showed shown side effects signaling significant studies suggested supplementation systemic tazarotene therapy tion tissue topical topical retinoids transcription treated treatment tretinoin trial tumor vitamin vitro vivo weeks
Popular passages
Page 328 - Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division.
Page 219 - Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin, N. Engl. J. Med., 318, 1633, 1988.
Page 74 - Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res.
Page 342 - Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans", Am J Clin Nutr. 71, 795-798 (2000). 12. J. Lee, S. Jiang, N. Levine, and R. Watson, "Carotenoid supplementation...
Page v - We trust that this volume will be of broad interest to scientists and clinicians alike. Alan R. Shalita SUNY Health Science Center Brooklyn, New York iii Series Editors ALAN R.