Developmental ToxicologyCarole A. Kimmel, Judy Buelke-Sam Raven Press, 1981 - 340 pages |
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Page 239
... animals , i.e. , tests that are compatible with the response capabilities of young animals ( 5,27,53,115 ) . Also , a life - span approach would require holding animals to old age for further testing , and this would be costly ...
... animals , i.e. , tests that are compatible with the response capabilities of young animals ( 5,27,53,115 ) . Also , a life - span approach would require holding animals to old age for further testing , and this would be costly ...
Page 244
... animals and not in preweaning or aged animals . This approach may provide data that show treated and control animals to be functionally similar or dissimilar as adults , but no information is obtained regarding the rate of development ...
... animals and not in preweaning or aged animals . This approach may provide data that show treated and control animals to be functionally similar or dissimilar as adults , but no information is obtained regarding the rate of development ...
Page 247
... animals ( 80 ) . Nagy and co - workers conducted a series of studies on the development of learning and memory in mice in the straight escape runway , a T maze , and a passive avoidance paradigm using procedures and performance ...
... animals ( 80 ) . Nagy and co - workers conducted a series of studies on the development of learning and memory in mice in the straight escape runway , a T maze , and a passive avoidance paradigm using procedures and performance ...
Contents
Biochemical Mechanisms in Developmental Toxicology | 1 |
Comparative Development of Specific Organ Systems | 13 |
Comparative Placental Morphology and Function | 35 |
Copyright | |
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abnormalities action activity addition adult agents alterations animals appear approach associated behavioral binding Biochem birth blood carcinogens cells changes chemical cleft palate compared complex compounds considered culture demonstrated detection determine developmental differentiation disease dose drug early edited effects embryos enzyme evaluation example experimental exposed exposure factors female fetal function genetic gestation growth hepatic hormones human immune important increase indicated induced influence interaction involves levels limb liver males malformations maternal maturation measurement mechanisms membrane metabolism methods mice mouse neonatal normal observed occurs offspring ontogeny organ perinatal period Pharmacol placental possible postnatal potential pregnancy prenatal present Press produced protein rats reactions receptor relatively reproductive response risk screening selected sensitivity similar specific stage strains studies suggested Table teratogenic Teratology tissues toxicity Toxicology transplacental treatment tumors urogenital sinus weeks York