Streptococcal Infections: Clinical Aspects, Microbiology, and Molecular PathogenesisDennis L. Stevens, Edward L. Kaplan Oxford University Press, 2000 - 449 pages Streptococcal Infections: Clinical Aspects, Microbiology, and Molecular Pathogenesis offers an in-depth examination of the spectrum of hemolytic streptococcal infections and their complications. Additionally, the volume incorporates and discusses aspects of pneumococcal, entrococcal, and oral streptococcal disease. The recent resurgence of rheumatic fever, concomitant outbreaks of severe systemic group A streptococcal infections (often accompanied by toxic shock), an increasing incidence of multiple antibiotic resistance among streptococcal species, and an intensified effort to develop effective streptococcal vaccines have brought renewed attention to the continuing role of streptococci for causing significant medical and public health problems in both industrialized and developing countries. Addressing clinical and epidemiological aspects, and microbiological and other approaches of the research scientist, this volume is the first to comprehensively address these clinically important organisms in many years. The contributors are internationally recognized for their expertise, making this book invaluable for infectious disease physicians, (internists, pediatricians, and family physicians, microbiologists, epidemiologists, and basic scientists with an interest in streptococcal infections and their complications. |
Contents
History of Hemolytic Streptococci and Associated Diseases | 1 |
Group A BetaHemolytic Streptococci Virulence Factors Pathogenesis and Spectrum of Clinical Infections | 19 |
Group A Streptococcal Genetics and Virulence | 37 |
Exotoxins of Streptococcus pyogenes | 57 |
Streptococcal Pharyngitis | 76 |
Rheumatic Fever Pathogenesis | 102 |
Rheumatic Fever | 133 |
Streptococcal Pyoderma | 144 |
Group C and G Streptococci | 238 |
Nonhemolytic Streptococci | 255 |
Laboratory Evaluation of Streptococci | 266 |
Enterococcal Infections | 280 |
Streptococcus pneumoniae Infections | 302 |
Oral Streptococci in Health and Disease | 333 |
Protection Against Group A Streptococcal Infection | 371 |
Multivalent Group A Streptococcal Vaccines | 390 |
Acute Poststreptococcal Glomerulonephritis | 152 |
LifeThreatening Streptococcal Infections Scarlet Fever Necrotizing Fasciitis Myositis Bacteremia and Streptococcal Toxic Shock Syndrome | 163 |
Molecular Pathogenesis of Group B Streptococcal Disease in Newborns | 180 |
Group B Streptococcal Infections | 222 |
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Common terms and phrases
activity acute rheumatic fever adhesin adults amino acid anti antibiotics antibodies antigen antimicrobial associated bacteremia bacterial binding Biol blood capsule carditis Clin Microbiol clinical Cloning coccal cocci coccus colonization conjugate cross-reactive culture disease endocarditis enterococci epitopes exotoxin factors fections Fischetti GABHS gene genetic glomerulonephritis group A streptococci group G heart hemolytic host human immune response Immunol impetigo infants Infect Immun invasive isolates Kasper DL Lancefield membrane meningitis mice molecular molecule mucosal myosin necrotizing fasciitis neonatal opsonic oral pathogenesis pathogens patients Pediatr penicillin peptide pharyngitis pneu pneumococcal polysaccharide produce protein pyrogenic exotoxin resistance role scarlet fever Schlievert PM sepsis sequence serotypes serum skin specific Stevens DL strains strep strepto streptococcal infections streptococcal M protein streptococcal pharyngitis Streptococcus mutans Streptococcus pneumoniae Streptococcus pyogenes Streptococcus sanguis streptolysin studies superantigen syndrome tein therapy tion tissue tococcal toxic toxin treatment type-specific vaccine viridans streptococci virulence vitro