The Laboratory Rat: Research applicationsHenry J. Baker, James Russell Lindsey, Steven H. Weisbroth Academic Press, 1979 - 276 pages |
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Page 114
... toxicity data from related chemicals . doses of the test compounds that otherwise might become toxic due to retention in the body . Even if these physiological dif- ferences were minimal , a paramount difference between man and the ...
... toxicity data from related chemicals . doses of the test compounds that otherwise might become toxic due to retention in the body . Even if these physiological dif- ferences were minimal , a paramount difference between man and the ...
Page 116
... toxicity trials and on those involving reproduction , mutagenicity , and carcinogenicity . Following completion of the long - term toxicity studies , the studies dealing with repro- duction , teratogenic , perinatal and postnatal ...
... toxicity trials and on those involving reproduction , mutagenicity , and carcinogenicity . Following completion of the long - term toxicity studies , the studies dealing with repro- duction , teratogenic , perinatal and postnatal ...
Page 117
... toxicity evaluations . E. Environmental Contaminants Recently enacted clean air and clean water legislation ( 11,23 ) will require that oral and inhalation toxicity studies in rats be performed on compounds found to be polluting the ...
... toxicity evaluations . E. Environmental Contaminants Recently enacted clean air and clean water legislation ( 11,23 ) will require that oral and inhalation toxicity studies in rats be performed on compounds found to be polluting the ...
Contents
Substance Administration | 19 |
THE LABORATORY RAT VOL II Copyright 1980 by Academic Press | 43 |
List of Contributors | 75 |
Copyright | |
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Academic Press adult agents Anat anesthesia anesthetic animal model antibody antigens Arch artery biochemical Biol blastocyst blood pressure BN/Bi body weight cage Cancer Inst Cancer Res carcinogenesis carcinogens carcinomas cardiac caries cavity cells chemical chronic Clin dental caries diet disease dose drug duct effects embryo enzyme euthanasia evaluation experimental exposure factors female genetic germfree germfree rats GF rats gland gnotobiotic heart histocompatibility human hypertension IARC IARC Sci immune immunoglobulin Immunol implantation inbred induced infection intravenous isolator laboratory animals laboratory rat lesions leukemia liver lymph lymphocytes male malformations mammary metabolism method mg/kg molars mouse myocardium myocytes N. Y. Acad Natl neoplasms normal oral Pathol Pathology Physiol placenta Proc procedure protein response rodents specific spontaneous Sprague-Dawley studies technique teratogenic Teratology thoracic duct tion tissue toxicity transplantable trypan blue tumors vitro WAG/Rij Wistar Wistar rats yolk sac