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Page 114
With the advent of increased pharmacological and metabolism data , rationale for dose selection , and statistical sophistication and computer techniques , the specific toxicity data from related chemicals . LD3 , dose level is now often ...
With the advent of increased pharmacological and metabolism data , rationale for dose selection , and statistical sophistication and computer techniques , the specific toxicity data from related chemicals . LD3 , dose level is now often ...
Page 116
Studies would be continuing during this time on with the intent of exempting these materials from extensive the chronic toxicity trials and on those involving reproduction , toxicity testing , reevaluation of many of these chemicals has ...
Studies would be continuing during this time on with the intent of exempting these materials from extensive the chronic toxicity trials and on those involving reproduction , toxicity testing , reevaluation of many of these chemicals has ...
Page 117
submission of toxicity information to regulatory agencies . This Welfare Act and the “ Guide for the Care and Use of Laboraact is promulgated by the EPA and requires essentially the tory Animals " ( 34 ) .
submission of toxicity information to regulatory agencies . This Welfare Act and the “ Guide for the Care and Use of Laboraact is promulgated by the EPA and requires essentially the tory Animals " ( 34 ) .
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Contents
Identification Methods | 4 |
Specimen Collection | 5 |
Substance Administration | 19 |
Copyright | |
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Acad activity addition administration adult agents antigens appear Arch artery Biol blood body cage Cancer Cancer Res carcinogenesis carcinogens carcinomas caries cells changes chemical collection compared compounds described determined diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland growth heart human hypertension incidence increased induced infection isolated laboratory animals laboratory rat lesions liver lymphocytes male material method mg/kg mice months normal observed obtained occur oral organ Pathology period Physiol placed placenta potential present Press pressure Proc procedure produced Reference reported response selected species specific spontaneous strain studies Table technique teratogenic tion tissue toxicity transplantable tumors types usually various volume weeks weight Wistar York