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Page 104
I. INTRODUCTION GENERAL CONSIDERATIONS IN SELECTING ANIMALS FOR TOXICOLOGICAL RESEARCH The biological effects of chemicals are determined by the dose of the chemical applied ( 9 ) . It is the responsibility of the Species selection of ...
I. INTRODUCTION GENERAL CONSIDERATIONS IN SELECTING ANIMALS FOR TOXICOLOGICAL RESEARCH The biological effects of chemicals are determined by the dose of the chemical applied ( 9 ) . It is the responsibility of the Species selection of ...
Page 105
Test performed or system tested Recommended procedure A variety of factors influence the proper selection of the animal model . Usually more than one species is selected when Screening tests using healthy rats evaluating a specific ...
Test performed or system tested Recommended procedure A variety of factors influence the proper selection of the animal model . Usually more than one species is selected when Screening tests using healthy rats evaluating a specific ...
Page 229
less than 5 weeks , more than 5 weeks old , male and female ; selected for susceptibility to infection blood 6 months after infection ; fragments of adult worm from one rat . Adult worms present in 36 % of young male rats ; 10 % of old ...
less than 5 weeks , more than 5 weeks old , male and female ; selected for susceptibility to infection blood 6 months after infection ; fragments of adult worm from one rat . Adult worms present in 36 % of young male rats ; 10 % of old ...
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Contents
Identification Methods | 4 |
Specimen Collection | 5 |
Substance Administration | 19 |
Copyright | |
14 other sections not shown
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Acad activity addition administration adult agents antigens appear Arch artery Biol blood body cage Cancer Cancer Res carcinogenesis carcinogens carcinomas caries cells changes chemical collection compared compounds described determined diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland growth heart human hypertension incidence increased induced infection isolated laboratory animals laboratory rat lesions liver lymphocytes male material method mg/kg mice months normal observed obtained occur oral organ Pathology period Physiol placed placenta potential present Press pressure Proc procedure produced Reference reported response selected species specific spontaneous strain studies Table technique teratogenic tion tissue toxicity transplantable tumors types usually various volume weeks weight Wistar York