The Laboratory Rat: Research applicationsHenry J. Baker, James Russell Lindsey, Steven H. Weisbroth Academic Press, 1979 - 276 pages |
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Page 123
... occur in animals exposed to chemicals as well as in nontreated animals , the oncologist must know the type and incidence of spontaneously occurring tumors and related hyperplasias for the strain of rat being used and the usual time of ...
... occur in animals exposed to chemicals as well as in nontreated animals , the oncologist must know the type and incidence of spontaneously occurring tumors and related hyperplasias for the strain of rat being used and the usual time of ...
Page 130
... occur with a frequency of 1 % or less ( 211 ) . With the discovery of an efficient colon carcinogen , 1,2- dimethylhydrazine ( DMH ) , the incidence has been increased to 100 % . Other tumors produced by DMH occur in the small intestine ...
... occur with a frequency of 1 % or less ( 211 ) . With the discovery of an efficient colon carcinogen , 1,2- dimethylhydrazine ( DMH ) , the incidence has been increased to 100 % . Other tumors produced by DMH occur in the small intestine ...
Page 132
... occur in both the subcutis and body cavities . Consid- erable research has been directed to define the mechanisms of soft tissue carcinogenesis , especially in the area of foreign body - induced sarcomas and solid state or smooth ...
... occur in both the subcutis and body cavities . Consid- erable research has been directed to define the mechanisms of soft tissue carcinogenesis , especially in the area of foreign body - induced sarcomas and solid state or smooth ...
Contents
Substance Administration | 19 |
THE LABORATORY RAT VOL II Copyright 1980 by Academic Press | 43 |
List of Contributors | 75 |
Copyright | |
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Academic Press adult agents Anat anesthesia anesthetic animal model antibody antigens Arch artery biochemical Biol blastocyst blood pressure BN/Bi body weight cage Cancer Inst Cancer Res carcinogenesis carcinogens carcinomas cardiac caries cavity cells chemical chronic Clin dental caries diet disease dose drug duct effects embryo enzyme euthanasia evaluation experimental exposure factors female genetic germfree germfree rats GF rats gland gnotobiotic heart histocompatibility human hypertension IARC IARC Sci immune immunoglobulin Immunol implantation inbred induced infection intravenous isolator laboratory animals laboratory rat lesions leukemia liver lymph lymphocytes male malformations mammary metabolism method mg/kg molars mouse myocardium myocytes N. Y. Acad Natl neoplasms normal oral Pathol Pathology Physiol placenta Proc procedure protein response rodents specific spontaneous Sprague-Dawley studies technique teratogenic Teratology thoracic duct tion tissue toxicity transplantable trypan blue tumors vitro WAG/Rij Wistar Wistar rats yolk sac