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Page 110
... Administration Guidelines for Animal Toxicity Studies Requirements for subacute or chronic toxicity studies Category Duration of human administration Study phase Oral or parenteral Several days As long as 2 weeks As long as 3 months ...
... Administration Guidelines for Animal Toxicity Studies Requirements for subacute or chronic toxicity studies Category Duration of human administration Study phase Oral or parenteral Several days As long as 2 weeks As long as 3 months ...
Page 154
12 18 24 30 36 42 48 Age ( months ) Fig . 3. Mortality curves from cohorts of female BN / Bi and WAG / Rij virgin and retired breeder rats . > 9 III . HOW OLD IS AN OLD RAT ? generalization that retired breeders do not live as long as ...
12 18 24 30 36 42 48 Age ( months ) Fig . 3. Mortality curves from cohorts of female BN / Bi and WAG / Rij virgin and retired breeder rats . > 9 III . HOW OLD IS AN OLD RAT ? generalization that retired breeders do not live as long as ...
Page 229
Angiostrongylus mackerrasae " White " rat , laboratory - bred , 3-6 months old Third - stage larva , oral . Glaxo strain , 170-200 gm Anisakis simplex ( ? ) ( from mesenteries of herring ) Larva ( stage not known ) , oral .
Angiostrongylus mackerrasae " White " rat , laboratory - bred , 3-6 months old Third - stage larva , oral . Glaxo strain , 170-200 gm Anisakis simplex ( ? ) ( from mesenteries of herring ) Larva ( stage not known ) , oral .
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Contents
Identification Methods | 4 |
Specimen Collection | 5 |
Substance Administration | 19 |
Copyright | |
14 other sections not shown
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Common terms and phrases
Acad activity addition administration adult agents antigens appear Arch artery Biol blood body cage Cancer Cancer Res carcinogenesis carcinogens carcinomas caries cells changes chemical collection compared compounds described determined diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland growth heart human hypertension incidence increased induced infection isolated laboratory animals laboratory rat lesions liver lymphocytes male material method mg/kg mice months normal observed obtained occur oral organ Pathology period Physiol placed placenta potential present Press pressure Proc procedure produced Reference reported response selected species specific spontaneous strain studies Table technique teratogenic tion tissue toxicity transplantable tumors types usually various volume weeks weight Wistar York
Bibliographic information
| Title | The Laboratory Rat: Research applications Volume 2 of American College of Laboratory Animal Medicine series, American College of Laboratory Animal Medicine Volume 2 of The Laboratory Rat, Steven H. Weisbroth The Laboratory Rat: Research Applications V. II, James Russell Lindsey |
| Editors | Henry J. Baker, James Russell Lindsey, Steven H. Weisbroth |
| Edition | illustrated |
| Publisher | Academic Press, 1979 |
| Original from | the University of Michigan |
| Digitized | 16 Jul 2008 |
| ISBN | 0120749025, 9780120749027 |
| Length | 276 pages |
| Export Citation | BiBTeX EndNote RefMan |