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Page 109
Production of a sample of test material to be used for normal and diseased human patients to determine the efficacy animal and clinical research studies . 3. Perform analytical chemistry procedures to identify the of the new drug .
Production of a sample of test material to be used for normal and diseased human patients to determine the efficacy animal and clinical research studies . 3. Perform analytical chemistry procedures to identify the of the new drug .
Page 132
Lesions in rats inocuproduced by essentially inert , insoluble materials such as glass , lated at 4 days of age were ... the same material was implanted in powdered , of polyoma virus ( 170 ) . finely shredded , or perforated forms .
Lesions in rats inocuproduced by essentially inert , insoluble materials such as glass , lated at 4 days of age were ... the same material was implanted in powdered , of polyoma virus ( 170 ) . finely shredded , or perforated forms .
Page 171
There are diffuse expansions of dense Z band material ( arrow ) . Scale , 1 um . Inset shows higher magnification of expanded Z band material ( Z ' ) present in SHR with cardiac hypertrophy . Scale , 1 um . [ From Kawamura et al .
There are diffuse expansions of dense Z band material ( arrow ) . Scale , 1 um . Inset shows higher magnification of expanded Z band material ( Z ' ) present in SHR with cardiac hypertrophy . Scale , 1 um . [ From Kawamura et al .
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Contents
Identification Methods | 4 |
Specimen Collection | 5 |
Substance Administration | 19 |
Copyright | |
14 other sections not shown
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Common terms and phrases
Acad activity addition administration adult agents antigens appear Arch artery Biol blood body cage Cancer Cancer Res carcinogenesis carcinogens carcinomas caries cells changes chemical collection compared compounds described determined diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland growth heart human hypertension incidence increased induced infection isolated laboratory animals laboratory rat lesions liver lymphocytes male material method mg/kg mice months normal observed obtained occur oral organ Pathology period Physiol placed placenta potential present Press pressure Proc procedure produced Reference reported response selected species specific spontaneous strain studies Table technique teratogenic tion tissue toxicity transplantable tumors types usually various volume weeks weight Wistar York
Bibliographic information
| Title | The Laboratory Rat: Research applications Volume 2 of American College of Laboratory Animal Medicine series, American College of Laboratory Animal Medicine Volume 2 of The Laboratory Rat, Steven H. Weisbroth The Laboratory Rat: Research Applications V. II, James Russell Lindsey |
| Editors | Henry J. Baker, James Russell Lindsey, Steven H. Weisbroth |
| Edition | illustrated |
| Publisher | Academic Press, 1979 |
| Original from | the University of Michigan |
| Digitized | 16 Jul 2008 |
| ISBN | 0120749025, 9780120749027 |
| Length | 276 pages |
| Export Citation | BiBTeX EndNote RefMan |