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Page 109
more than 10 million dollars to develop a single new drug . As 7. Conduct preclinical toxicity tests in laboratory animals an average , more than 5000 chemicals are synthesized and and submit these data along with data from the studies ...
more than 10 million dollars to develop a single new drug . As 7. Conduct preclinical toxicity tests in laboratory animals an average , more than 5000 chemicals are synthesized and and submit these data along with data from the studies ...
Page 115
The development of time compatible with that for which the drug might be used of strains with unusual growth ... These tests are specifically re- bacteria following chemically induced chromosomal alteraquired for drugs which will be ...
The development of time compatible with that for which the drug might be used of strains with unusual growth ... These tests are specifically re- bacteria following chemically induced chromosomal alteraquired for drugs which will be ...
Page 118
In “ The Physiological Equivalence of Drug Dosing Forms , ” Food and Drug Directorate , Ottawa , Canada . 7. Brodie , B. B. , and Reid , W. D. ( 1969 ) . Is man a unique animal in response to drugs ? Am . J. Pharm . 141 , 21-26 . 8.
In “ The Physiological Equivalence of Drug Dosing Forms , ” Food and Drug Directorate , Ottawa , Canada . 7. Brodie , B. B. , and Reid , W. D. ( 1969 ) . Is man a unique animal in response to drugs ? Am . J. Pharm . 141 , 21-26 . 8.
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Contents
Identification Methods | 4 |
Specimen Collection | 5 |
Substance Administration | 19 |
Copyright | |
14 other sections not shown
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Acad activity addition administration adult agents antigens appear Arch artery Biol blood body cage Cancer Cancer Res carcinogenesis carcinogens carcinomas caries cells changes chemical collection compared compounds described determined diet disease dose drug duct effects embryo evaluation experimental experiments exposure factors female function genetic germfree gland growth heart human hypertension incidence increased induced infection isolated laboratory animals laboratory rat lesions liver lymphocytes male material method mg/kg mice months normal observed obtained occur oral organ Pathology period Physiol placed placenta potential present Press pressure Proc procedure produced Reference reported response selected species specific spontaneous strain studies Table technique teratogenic tion tissue toxicity transplantable tumors types usually various volume weeks weight Wistar York