The Laboratory Rat, Volume 2Henry J. Baker, J. Russell Lindsey, Steven H. Weisbroth Academic Press, 1980 - 276 pages |
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Page 112
... dose , 14 - day observation Mice 50-60 50-60 50-60 6-8 Dose range , 14 days consecutive dosing Subchronic studies 30 - day preclinical 90 - day subchronic Chronic studies 6 months to 1 year dosing Carcinogenicity studies 18 months to 24 ...
... dose , 14 - day observation Mice 50-60 50-60 50-60 6-8 Dose range , 14 days consecutive dosing Subchronic studies 30 - day preclinical 90 - day subchronic Chronic studies 6 months to 1 year dosing Carcinogenicity studies 18 months to 24 ...
Page 114
... dose group being increased in a geometric or logarithmic fashion until toxic effects occur . E. Subchronic Toxicity Studies These studies are designed to provide data on the toxic ef- fects of the new drug and to determine the dose ...
... dose group being increased in a geometric or logarithmic fashion until toxic effects occur . E. Subchronic Toxicity Studies These studies are designed to provide data on the toxic ef- fects of the new drug and to determine the dose ...
Page 265
... Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Given B.I.D. ...
... Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Given B.I.D. ...
Contents
Substance Administration | 19 |
THE LABORATORY RAT VOL II Copyright 1980 by Academic Press | 43 |
List of Contributors | 75 |
Copyright | |
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The Laboratory Rat, Volume 2 Henry J. Baker,J. Russell Lindsey,Steven H. Weisbroth Snippet view - 1980 |
Common terms and phrases
Academic Press adult agents Anat anesthesia anesthetic animal model antibody antigens Arch artery biochemical Biol blastocyst blood pressure BN/Bi body weight cage Cancer Inst Cancer Res carcinogenesis carcinogens carcinomas cardiac caries cavity cells chemical chronic Clin dental caries diet disease dose drug duct effects embryo enzyme euthanasia evaluation experimental exposure factors female genetic germfree germfree rats GF rats gland gnotobiotic heart histocompatibility human hypertension IARC IARC Sci immune immunoglobulin Immunol implantation inbred induced infection intravenous isolator laboratory animals laboratory rat lesions leukemia liver lymph lymphocytes male malformations mammary metabolism method mg/kg molars mouse myocardium myocytes N. Y. Acad Natl neoplasms normal oral Pathol Pathology Physiol placenta Proc procedure protein response rodents specific spontaneous Sprague-Dawley studies technique teratogenic Teratology thoracic duct tion tissue toxicity transplantable trypan blue tumors vitro WAG/Rij Wistar Wistar rats yolk sac
Bibliographic information
| Title | The Laboratory Rat, Volume 2 American College of Laboratory Animal Medicine series The laboratory rat |
| Editors | Henry J. Baker, J. Russell Lindsey, Steven H. Weisbroth |
| Contributor | American College of Laboratory Animal Medicine |
| Publisher | Academic Press, 1980 |
| Original from | the University of Michigan |
| Digitized | 16 Jul 2008 |
| ISBN | 0120749025, 9780120749027 |
| Length | 276 pages |
| Export Citation | BiBTeX EndNote RefMan |