The Laboratory Rat: Research applicationsHenry J. Baker, James Russell Lindsey, Steven H. Weisbroth Academic Press, 1979 - 276 pages |
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Page 87
... dose on a given day ( acute expo- sure ) , or to treat with multiple doses over several days ( chronic exposure ) . It is difficult to have a truly acute experiment , since once an agent is administered it may not be known how long the ...
... dose on a given day ( acute expo- sure ) , or to treat with multiple doses over several days ( chronic exposure ) . It is difficult to have a truly acute experiment , since once an agent is administered it may not be known how long the ...
Page 114
... dose selection , and toxicity data from related chemicals . doses of the test compounds that otherwise might become toxic due to retention in the body . Even if these physiological dif- ferences were minimal , a paramount difference ...
... dose selection , and toxicity data from related chemicals . doses of the test compounds that otherwise might become toxic due to retention in the body . Even if these physiological dif- ferences were minimal , a paramount difference ...
Page 265
... Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Given B.I.D. ...
... Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Dose prevented body weight gain Given B.I.D. ...
Contents
Substance Administration | 19 |
THE LABORATORY RAT VOL II Copyright 1980 by Academic Press | 43 |
List of Contributors | 75 |
Copyright | |
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Academic Press adult agents Anat anesthesia anesthetic animal model antibody antigens Arch artery biochemical Biol blastocyst blood pressure BN/Bi body weight cage Cancer Inst Cancer Res carcinogenesis carcinogens carcinomas cardiac caries cavity cells chemical chronic Clin dental caries diet disease dose drug duct effects embryo enzyme euthanasia evaluation experimental exposure factors female genetic germfree germfree rats GF rats gland gnotobiotic heart histocompatibility human hypertension IARC IARC Sci immune immunoglobulin Immunol implantation inbred induced infection intravenous isolator laboratory animals laboratory rat lesions leukemia liver lymph lymphocytes male malformations mammary metabolism method mg/kg molars mouse myocardium myocytes N. Y. Acad Natl neoplasms normal oral Pathol Pathology Physiol placenta Proc procedure protein response rodents specific spontaneous Sprague-Dawley studies technique teratogenic Teratology thoracic duct tion tissue toxicity transplantable trypan blue tumors vitro WAG/Rij Wistar Wistar rats yolk sac