The Laboratory Rat: Research applicationsHenry J. Baker, James Russell Lindsey, Steven H. Weisbroth Academic Press, 1979 - 276 pages |
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Page 104
... chemicals are determined by the dose of the chemical applied ( 9 ) . It is the responsibility of the science of toxicology to determine under what conditions and circumstances a certain chemical will be safe , beneficial , or ...
... chemicals are determined by the dose of the chemical applied ( 9 ) . It is the responsibility of the science of toxicology to determine under what conditions and circumstances a certain chemical will be safe , beneficial , or ...
Page 124
... chemical or of another chemical later in life , although the carcinogenic effect of the chemical is expressed in the same target organ . Prenatal exposure of rats to certain nitrosamines and nit- rosamides is followed by a high ...
... chemical or of another chemical later in life , although the carcinogenic effect of the chemical is expressed in the same target organ . Prenatal exposure of rats to certain nitrosamines and nit- rosamides is followed by a high ...
Page 134
... Chemical Agents Chemical carcinogens have both endogenous and exogenous origin and represent the largest group of known carcinogens . They are believed to be the cause of up to 90 % of cancer in man ( 120 ) . Exogenous sources of chemical ...
... Chemical Agents Chemical carcinogens have both endogenous and exogenous origin and represent the largest group of known carcinogens . They are believed to be the cause of up to 90 % of cancer in man ( 120 ) . Exogenous sources of chemical ...
Contents
Substance Administration | 19 |
THE LABORATORY RAT VOL II Copyright 1980 by Academic Press | 43 |
List of Contributors | 75 |
Copyright | |
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Academic Press adult agents Anat anesthesia anesthetic animal model antibody antigens Arch artery biochemical Biol blastocyst blood pressure BN/Bi body weight cage Cancer Inst Cancer Res carcinogenesis carcinogens carcinomas cardiac caries cavity cells chemical chronic Clin dental caries diet disease dose drug duct effects embryo enzyme euthanasia evaluation experimental exposure factors female genetic germfree germfree rats GF rats gland gnotobiotic heart histocompatibility human hypertension IARC IARC Sci immune immunoglobulin Immunol implantation inbred induced infection intravenous isolator laboratory animals laboratory rat lesions leukemia liver lymph lymphocytes male malformations mammary metabolism method mg/kg molars mouse myocardium myocytes N. Y. Acad Natl neoplasms normal oral Pathol Pathology Physiol placenta Proc procedure protein response rodents specific spontaneous Sprague-Dawley studies technique teratogenic Teratology thoracic duct tion tissue toxicity transplantable trypan blue tumors vitro WAG/Rij Wistar Wistar rats yolk sac