1. Do you have a minimum shipment limit (yes no X ), minimum dollar no X )? 2. 3. What discounts from your catalogue prices do you allow for minimum purchases What additional discounts are given for quantity a) Individually owned community pharmacies (discounts): Do not sell (additional discounts/quantity):_ b) Chain drug stores who maintain warehouse facilities (discount): (additional discounts/quantity): Do not sell 20% c) Conventional drug wholesalers (discount): (additional discounts/quantity): d) Physicians in individual private practice (discount): Do not sell (additional discounts/quantity): e) Privately owned medical clinics or proprietary hospitals (discount): 15% (additional discounts/quantity): f) Tax supported institutions, such as community, state or federal hospitals (discount): 20% (additional discounts/quantity): Does your company respond to bid offers from federal or state governments, hospitals or other large community purchasers? (yes X, no Please explain: Municipal, County, Federal and State Hospitals We regret that we cannot be of service in assisting you with 1. Do you have a minimum shipment limit (yes X, no ), minimum dollar no )? For prepaid transportation $25.00 Net for hospitals (See copy of Sales Policy attached.) minimum shipment of $50.00 Net for wholesalers; 2. 3. What discounts from your catalogue prices do you allow for minimum purchases by each of the following? What additional discounts are given for quantity purchases? a) Individually owned community pharmacies (discounts): We do not sell direct (additional discounts/quantity): to pharmacies. b) Chain drug stores who maintain warehouse facilities (discount):__We do (additional discounts/quantity): not sell to chain drug stores. c) Conventional drug wholesalers (discount): 52% off list prices (additional discounts/quantity):___ Quantity prices quoted net d) Physicians in individual private practice (discount):__Do not sell physicians (additional discounts/quantity): direct. e) Privately owned medical clinics or proprietary hospitals (discount): 46% (additional discounts/quantity): Quoted net. f) Tax supported institutions, such as community, state or federal hospitals (discount): 52% (additional discounts/quantity): Quoted net Does your company respond to bid offers from federal or state governments, hospitals or other large community purchasers? (yes X, no Please explain: LAKESIDE LABORATORIES, INC. Milwaukee, Wisconsin We offer: WHOLESALE DISTRIBUTOR SALES POLICY 52 percent from list price (except those bulk quantity prices indicated as net) plus a cash discount of 2 percent, 30 days from date of invoice, net 45 days. On automatic shipments to wholesale distributors we allow 90 days. DROP SHIPMENTS - Drop shipments, when necessary, will be honored and invoiced at 46 percent from list price. Bulk quantity drop shipments will be invoiced at net plus 10 percent. TRANSPORTATION- All shipments are prepaid. On orders less When special handling other than our usual routing is requested, charges in excess of the usual amount will be added to the invoice. Claim for damage or loss in shipment must be filed with Lakeside Laboratories, Inc., within ten days of delivery accompanied by a description of damage or loss, and substantiated by the carrier's freight bill. If damage is apparent, please request carrier to note, "Received in bad condition", on freight bill before accepting delivery. RETURN GOODS - Unbroken, unopened packages of unsalable merchan- DISTRIBUTION - Lakeside products are available to retail pharmacies only through select, accredited service wholesalers. May 1964 NORPRAMIN® (desipramine hydrochloride) DESCRIPTION: Each round lemon-yellow biconvex tablet contains: Chemically: .25 mg. 10, 11-dihydro-5-(3-methylaminopropyl)-5H-dibenz (b, f) azepine hydrochloride IN BRIEF Action and Uses: Norpramin (desipramine hydrochloride) is the primary active metabolite of imipramine. It differs from earlier antidepressants in its rapid onset of action. Approximately 60 to 70% of patients with neurotic or psychotic depressions will respond satisfactorily. More than half will begin to improve in 2-5 days, others within a week. Usually, patients not responding within one week are less likely to improve. Indications: Norpramin is useful in the treatment of neurotic and psychotic depressive reactions, and in manic depressive or involutional psychotic reactions. It may be used as co-therapy with tranquilizers in the treatment of markedly agitated forms of depressions. Contraindications: (1) Norpramin should not be given within two weeks of treatment with a monoamine oxidase inhibitor. (2) Because of its autonomic effects, it is contraindicated in patients with glaucoma, urethral or ureteral spasm and recent myocardial infarction. (3) Severe coronary heart disease because of possible tachycardia. (4) Active epilepsy as it lowers the threshold for epileptiform seizures. Precautions: (1) Norpramin treatment should not be substituted for hospitalization or restraint if the risk of homicide or suicide is considered grave. (2) In patients with manic depressive illness, Norpramin may induce a hypomanic state after the depressive phase terminates. (3) Although animal teratology studies proved negative, further clinical experience is necessary to establish safety in human pregnancy. (4) Discontinue therapy prior to elective surgery. Adverse Effects: Mild side effects may occur in about 1 of 4 patients. These are usually well tolerated. Side effects include: dry mouth, constipation, dizziness, palpitation, delayed urination, "bad taste", sensory illusion, tinnitus, agitation and stimulation, sweating, drowsiness, headache, orthostatic hypotension, flushing, nausea, cramps, weakness, blurred vision and mydriasis, rash, allergy, altered liver function, ataxia and extrapyramidal signs. Dosage and Administration: Optimal results are obtained at about 150 mg./day. Dosage over 200-225 mg./day increases incidence of side effects. Norpramin may be administered as follows: two tablets (50 mg.) t.i.d. (150 mg./day). Partial response may be expected within 2-5 days; optimal response within 2-3 weeks. After optimal results are achieved a maintenance dose . . . 50-100 mg./day ... should be sought. Supplied: Norpramin (desipramine hydrochloride) tablets of 25 mg., in bottles of 50 and 500. |