Antihypertensive Drugs

Front Cover
CRC Press, 1997 M09 5 - 704 pages
Twenty US and European contributors from academia and pharmaceutical companies present a tripartite discussion of the short but impressive history of drug treatment of essential hypertension, focusing on: medicinal chemistry, pharmacology, and the clinical picture. Each successive generation of drugs (e.g. beta-blockers, calcium antagonists, and ACE-inhibitors) permits more precise tailoring to individual patient needs, as well as further elucidating the pathophysiology of the disease. Those interested in integrative medicine will appreciate the paper on treating hypertension in the elderly and diabetics, which refers to non-drug lifestyle approaches to lowering blood pressure. Annotation copyrighted by Book News, Inc., Portland, OR

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Contents

Renin Inhibitors
77
Neural Endopeptidase Inhibitors and Combined Inhibitors
113
Endothelin Blockade and Hypertension
213
Antihypertensive Drugs Interacting with Sympathetic Neurons
281
Vasodilators and Calcium Antagonists
313
Pharmacological Intervention in the ReninAngiotensin System
377
New Antihypertensive Drugs
409
Clinical Pharmacology of Current Antihypertensive Drugs
427
Hemodynamic Profile of Antihypertensive Drugs
463
Present Status and Future
483
Drug Treatment of Hypertension in the Elderly and in Diabetics
501
Index
529
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