Extrapolation Practice for Ecotoxicological Effect Characterization of ChemicalsKeith R. Solomon, Theo C.M. Brock, Dick De Zwart, Scott D. Dyer, Leo Posthuma, Sean Richards, Hans Sanderson, Paul Sibley, Paul J. van den Brink CRC Press, 2008 M05 23 - 408 pages A wide-ranging compilation of techniques, Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals describes methods of extrapolation in the framework of ecological risk assessment. The book, informally known as EXPECT, identifies data needs and situations where these extrapolations can be most usefully applied, makin |
Contents
Chapter 2 Matrix and Media Extrapolation | 33 |
Chapter 3 QSAR and Extrapolation | 75 |
Chapter 4 Extrapolation of Effects Measures across Levels of Biological Organization in Ecological Risk Assessment | 105 |
Chapter 5 Mixture Extrapolation Approaches | 135 |
Chapter 6 Temporal Extrapolation in Ecological Effect Assessment of Chemicals | 187 |
Chapter 7 Spatial Extrapolation in Ecological Effect Assessment of Chemicals | 223 |
Chapter 8 Conclusions | 257 |
Chapter 9 Glossary | 269 |
Chapter 10 Guidance on the Application of Extrapolation Methods in Ecological Exposure and Effects Characterization of Chemicals | 281 |
References | 323 |
Index | 369 |
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Common terms and phrases
acute analysis applied approach aquatic biological calculated cause Chapter chemicals chronic combined compared complex compounds concentration concentration addition considered contaminants dependent derived described developed direct distribution ecological ecological risk ecosystem ecotoxicology editors effects endpoints Environ Environ Toxicol Chem environmental estimates et al evaluation example existing experimental experiments exposed exposure extrapolation factors field Figure fish freshwater function groups higher impact important increase indicate individual influence interactions issues laboratory landscape less limited matrix measured metals methods microcosms mixture mode of action natural observed occur organisms pesticides populations possible potential practical predicted present problem properties Protection Q)SAR questions range recovery relationship relative response risk assessment sediment sensitivity similar soil spatial species Step stress stressors structure studies substances Table tiers tion toxicity types uncertainty USEPA validation values variability µg/L
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