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Page 178
While analgesic “ ceiling effects ” have not been established for the mixed agonist - antagonists , there is some question as to their maximal analgesic efficacy . Mixed agonist - antagonists have limited abuse - liability .
While analgesic “ ceiling effects ” have not been established for the mixed agonist - antagonists , there is some question as to their maximal analgesic efficacy . Mixed agonist - antagonists have limited abuse - liability .
Page 179
PHARMACOLOGIC ACTIONS OF NARCOTIC ANALGESICS Central Nervous System Effects Narcotic analgesics exert their primary effect on the central nervous system . The precise biochemical mechanism by which they produce their effects is presumed ...
PHARMACOLOGIC ACTIONS OF NARCOTIC ANALGESICS Central Nervous System Effects Narcotic analgesics exert their primary effect on the central nervous system . The precise biochemical mechanism by which they produce their effects is presumed ...
Page 184
Relative potency is , of course , merely an expression of the ratio of doses to produce a given effect , and a more potent ... However , among drugs of different classes , the spectra of side effects can be quite different and may be ...
Relative potency is , of course , merely an expression of the ratio of doses to produce a given effect , and a more potent ... However , among drugs of different classes , the spectra of side effects can be quite different and may be ...
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Contents
Prevalence and Profile of Pain | 21 |
Painful Complications of Cancer Diagnosis | 47 |
Issues in Cancer Pain Management | 69 |
Copyright | |
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achieved activity acute addition administration agents analgesia analgesic anxiety approach appropriate aspirin assessment associated attitudes behavioral cancer pain cancer patients cancer-related pain cause changes chronic pain Clin clinical compared complete component considered continuous dependence depression described developed direct discussed disease dose drugs effects et al evaluation example experience experienced factors frequently function given important increased indicated individual infusion initial intensity interventions involved knowledge less major measures medication methods morphine narcotic narcotic analgesics nerve nurses observed occur oncology oral pain control pain management pain relief pain syndromes percent possible postoperative potential present problem procedures produce progressive psychological radiation received recent relatively relaxation reported respiratory response result scale scores sensory severe side effects significant specific symptoms Table techniques terminal therapy tolerance treated treatment tumor usually York