The Laboratory RatMark A. Suckow, Steven H. Weisbroth, Craig L. Franklin Elsevier, 2005 M12 20 - 928 pages The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
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From inside the book
Page 78
... deficient rat; developed by Shumiya at Tokyo Metropoliton Institute of Gerontology as inbred strain from Nagase ... deficiency of lysosomal acid lipase; rats develop genetic lipid storage disease analogous to human Wolman's disease ...
... deficient rat; developed by Shumiya at Tokyo Metropoliton Institute of Gerontology as inbred strain from Nagase ... deficiency of lysosomal acid lipase; rats develop genetic lipid storage disease analogous to human Wolman's disease ...
Page 83
... deficiency, presumably due to a spontaneous mutation, C6m P77PMC albino Beijing Medical College from Wistar colony of unknown descent; rats develop audiogenic seizures (70%) and are susceptible to hyperthermia-induced (45 C) convulsions ...
... deficiency, presumably due to a spontaneous mutation, C6m P77PMC albino Beijing Medical College from Wistar colony of unknown descent; rats develop audiogenic seizures (70%) and are susceptible to hyperthermia-induced (45 C) convulsions ...
Page 84
... deficiency. TMB agouti hooded Irish Broadhurst from a stock selected by Tryon for good maze learning performance (Tryon maze bright). TMD black Broadhurst from a stock selected by Tryon for poor maze learning performance (Tryon maze ...
... deficiency. TMB agouti hooded Irish Broadhurst from a stock selected by Tryon for good maze learning performance (Tryon maze bright). TMD black Broadhurst from a stock selected by Tryon for poor maze learning performance (Tryon maze ...
Page 95
... deficiency results in acceleration of bone turnover and bone loss (Vanderschueren, 1996). Although the exact mechanism for bone loss related to androgen deficiency is unclear, it is associated with significant osteopenia (Erben et al ...
... deficiency results in acceleration of bone turnover and bone loss (Vanderschueren, 1996). Although the exact mechanism for bone loss related to androgen deficiency is unclear, it is associated with significant osteopenia (Erben et al ...
Page 142
... deficient rats were identified on Medline search (2004). Genetically modified mice and inbred dog breeds are used more ... Deficiency in vitamin K and administration of agents inhibitory to this enzyme complex, such as warfarin, lead to ...
... deficient rats were identified on Medline search (2004). Genetically modified mice and inbred dog breeds are used more ... Deficiency in vitamin K and administration of agents inhibitory to this enzyme complex, such as warfarin, lead to ...
Contents
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71 | |
93 | |
127 | |
147 | |
165 | |
8 Analysis of Behavior in Laboratory Rats | 191 |
9 Nutrition | 219 |
18 Experimental Modeling and Research Methodology | 587 |
19 Anesthesia and Analgesia | 627 |
20 Euthanasia and Necropsy | 665 |
21 Integrating Biology with Rat Genomic Tools | 679 |
22 Gnotobiotics | 693 |
23 Spontaneous Surgically and Chemically Induced Models of Disease | 711 |
24 The Nude Rat | 733 |
25 Gerontology and AgeAssociated Lesions | 761 |
10 Housing and Environment | 303 |
11 Bacterial Mycoplasmal and Mycotic Infections | 339 |
12 Viral Disease | 423 |
13 Parasitic Diseases | 453 |
14 Neoplastic Disease | 479 |
15 Metabolic Traumatic and Miscellaneous Diseases | 513 |
16 Medical Management and Diagnostic Approaches | 547 |
17 Occupational Health and Safety | 565 |
26 Cardiovascular Research | 773 |
27 Toxicology | 803 |
28 Embryology and Teratology | 817 |
29 Immunology | 847 |
30 Wild and Black Rats | 865 |
Appendix 1 Selected Normative Data | 883 |
Index | 885 |
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Common terms and phrases
acid activity albino altered appear associated behavior Biol blood body bone brain breeding cage calcium cancer cause cells changes chemical clinical colony compared concentrations containing decreased deficiency detection determine diet dietary disease effects environment et al experimental factors female function gene genetic gland glucose growth Health host housed human immune important inbred incidence increased indicate induced infection influence Institute intestinal involved iron isolated Laboratory Animal laboratory rats lesions levels liver male metabolism methods mice mouse natural normal Nutr Nutrition observed occur organism Pneumocystis Press prevent production protein rats fed reduced reported reproductive respiratory response rodents role selected serum showed shown species spontaneous strains studies tion tissue treatment tumors University virus vitamin Wistar