The Laboratory RatMark A. Suckow, Steven H. Weisbroth, Craig L. Franklin Elsevier, 2005 M12 20 - 928 pages The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
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From inside the book
Results 1-5 of 85
Page 55
... increased procedural monitoring, relief of pain and distress, and improved training for research personnel. Scientists, animal care personnel, regulators, and the public often have conflicting views on what constitutes appropriate care ...
... increased procedural monitoring, relief of pain and distress, and improved training for research personnel. Scientists, animal care personnel, regulators, and the public often have conflicting views on what constitutes appropriate care ...
Page 58
... increased incidence of foot lesions (ulcers and swelling) was reported in rats if they were housed on wire-bottom floors for more than a year (Peace et al., 2001). Conversely, Holson et al. (1991) studied adult rats housed long term in ...
... increased incidence of foot lesions (ulcers and swelling) was reported in rats if they were housed on wire-bottom floors for more than a year (Peace et al., 2001). Conversely, Holson et al. (1991) studied adult rats housed long term in ...
Page 59
... increased comfort or familiarity with the substance. Rats also preferred bedding materials composed of larger pieces, such as shavings or paper strips (PattersonKane, 2001b; Ras et al., 2002; van de Weerd et al., 1996). The use of nest ...
... increased comfort or familiarity with the substance. Rats also preferred bedding materials composed of larger pieces, such as shavings or paper strips (PattersonKane, 2001b; Ras et al., 2002; van de Weerd et al., 1996). The use of nest ...
Page 60
... increased circulating norepinephrine, epinephrine, and corticosterone levels. Some studies also have documented that social housing may lead to increased aggressive behavior, predominately in male rats (Galef and Sorge, 2000; Hurst et ...
... increased circulating norepinephrine, epinephrine, and corticosterone levels. Some studies also have documented that social housing may lead to increased aggressive behavior, predominately in male rats (Galef and Sorge, 2000; Hurst et ...
Page 67
... increased time in animal use protocol and program review by the IACUC, and tracking of animal numbers would drain resources from crucial ongoing and future research projects. Cost estimates of the paperwork burden alone ranged from $80 ...
... increased time in animal use protocol and program review by the IACUC, and tracking of animal numbers would drain resources from crucial ongoing and future research projects. Cost estimates of the paperwork burden alone ranged from $80 ...
Contents
53 | |
71 | |
93 | |
127 | |
147 | |
165 | |
8 Analysis of Behavior in Laboratory Rats | 191 |
9 Nutrition | 219 |
18 Experimental Modeling and Research Methodology | 587 |
19 Anesthesia and Analgesia | 627 |
20 Euthanasia and Necropsy | 665 |
21 Integrating Biology with Rat Genomic Tools | 679 |
22 Gnotobiotics | 693 |
23 Spontaneous Surgically and Chemically Induced Models of Disease | 711 |
24 The Nude Rat | 733 |
25 Gerontology and AgeAssociated Lesions | 761 |
10 Housing and Environment | 303 |
11 Bacterial Mycoplasmal and Mycotic Infections | 339 |
12 Viral Disease | 423 |
13 Parasitic Diseases | 453 |
14 Neoplastic Disease | 479 |
15 Metabolic Traumatic and Miscellaneous Diseases | 513 |
16 Medical Management and Diagnostic Approaches | 547 |
17 Occupational Health and Safety | 565 |
26 Cardiovascular Research | 773 |
27 Toxicology | 803 |
28 Embryology and Teratology | 817 |
29 Immunology | 847 |
30 Wild and Black Rats | 865 |
Appendix 1 Selected Normative Data | 883 |
Index | 885 |
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