The Laboratory RatMark A. Suckow, Steven H. Weisbroth, Craig L. Franklin Elsevier, 2005 M12 20 - 928 pages The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
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From inside the book
Results 1-5 of 92
Page 95
... decreased trabecular bone volume (Wronski et al., 1981); decreased bone formation owing in part to reduced osteoblast function (Carmeliet et al., 2001), which is independent of corticosteroid status (Zerath et al., 2000); and decreased ...
... decreased trabecular bone volume (Wronski et al., 1981); decreased bone formation owing in part to reduced osteoblast function (Carmeliet et al., 2001), which is independent of corticosteroid status (Zerath et al., 2000); and decreased ...
Page 135
... Decreased Red Cell Mass Most conditions resulting in decreased red cell mass are similar in the rat and other species. The generation of detailed sets of information from hematology analyzers provides the tools with which red cell ...
... Decreased Red Cell Mass Most conditions resulting in decreased red cell mass are similar in the rat and other species. The generation of detailed sets of information from hematology analyzers provides the tools with which red cell ...
Page 138
... decreased fluid intake. Prerenal and renal azotemia sometimes coexist, confounding interpretation. Azotemia may also occur with increased protein catabolism or with gastrointestinal bleeding. BUN and creatinine are relatively ...
... decreased fluid intake. Prerenal and renal azotemia sometimes coexist, confounding interpretation. Azotemia may also occur with increased protein catabolism or with gastrointestinal bleeding. BUN and creatinine are relatively ...
Page 141
... decreased numbers of lymphocytes and eosinophils. To document endocrine alterations in chronically stressed rats, serum adrenocorticotrophic hormone (ACTH) and corticosterone may be measured (Bamberg et al., 2001). These parameters are ...
... decreased numbers of lymphocytes and eosinophils. To document endocrine alterations in chronically stressed rats, serum adrenocorticotrophic hormone (ACTH) and corticosterone may be measured (Bamberg et al., 2001). These parameters are ...
Page 142
... decreased red cell mass is thought to result from decreased availability of Feþþ for erythropoiesis, decreased survival time of red blood cells, and decreased bone marrow production. The cytokines, IL-6, IL-1b, involved in the induction ...
... decreased red cell mass is thought to result from decreased availability of Feþþ for erythropoiesis, decreased survival time of red blood cells, and decreased bone marrow production. The cytokines, IL-6, IL-1b, involved in the induction ...
Contents
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71 | |
93 | |
127 | |
147 | |
165 | |
8 Analysis of Behavior in Laboratory Rats | 191 |
9 Nutrition | 219 |
18 Experimental Modeling and Research Methodology | 587 |
19 Anesthesia and Analgesia | 627 |
20 Euthanasia and Necropsy | 665 |
21 Integrating Biology with Rat Genomic Tools | 679 |
22 Gnotobiotics | 693 |
23 Spontaneous Surgically and Chemically Induced Models of Disease | 711 |
24 The Nude Rat | 733 |
25 Gerontology and AgeAssociated Lesions | 761 |
10 Housing and Environment | 303 |
11 Bacterial Mycoplasmal and Mycotic Infections | 339 |
12 Viral Disease | 423 |
13 Parasitic Diseases | 453 |
14 Neoplastic Disease | 479 |
15 Metabolic Traumatic and Miscellaneous Diseases | 513 |
16 Medical Management and Diagnostic Approaches | 547 |
17 Occupational Health and Safety | 565 |
26 Cardiovascular Research | 773 |
27 Toxicology | 803 |
28 Embryology and Teratology | 817 |
29 Immunology | 847 |
30 Wild and Black Rats | 865 |
Appendix 1 Selected Normative Data | 883 |
Index | 885 |
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