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abnormal activity Affective Disorder Alcohol American Psychiatric Association antidepressant anxiety disorders areas basal ganglia behavior biological factors biology of mental bipolar disorder brain budget cells centers chemical chromosome clinical research clozapine costs D/ART program decreased Department of Health diagnostic disease dopamine Drug Abuse episodes eugenic families Federal frontal cortex function funding gene Health and Human Human Services increased individuals with mental inheritance Institute of Mental involved issues Journal of Psychiatry limbic system locus ceruleus major depression manic marker mental disorders Mental Health Mental Illness million Miss Frumkin mood disorders National Institute neuron neuroscience research neurotransmitter NIMH norepinephrine obsessions Obsessive-Compulsive Disorder Office of Technology panic attacks panic disorder patients percent phrenia receptors research into mental research training result role schizo Science serotonin severe mental disorders social SOURCE specific stigma suicide Technology Assessment tion tissue trait treatment twins typical antipsychotic U.S. Department Washington
Page 55 - Five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1 ) depressed mood or (2) loss of interest or pleasure.
Page 55 - In children and adolescents, can be irritable mood. 2) markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day...
Page 55 - Insomnia or hypersomnia nearly every day 5 Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down) 6 Fatigue or loss of energy nearly every day 7 Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick...
Page 55 - The mood disturbance is sufficiently severe to cause marked impairment in occupational functioning or in usual social activities or relationships with others, or to necessitate hospitalization to prevent harm to self or others, or there are psychotic features.
Page 9 - It may be more accurate to say that despair, owing to some evil trick played upon the sick brain by the inhabiting psyche, comes to resemble the diabolical discomfort of being imprisoned in a fiercely overheated room. And because no breeze stirs this caldron, because there is no escape from this smothering confinement, it is entirely natural that the victim begins to think ceaselessly of oblivion.
Page 62 - B. At some point during the course of the disorder, the person has recognized that the obsessions or compulsions are excessive or unreasonable.
Page 54 - It was not really alarming at first, since the change was subtle, but I did notice that my surroundings took on a different tone at certain times: the shadows of nightfall seemed more somber, my mornings were less buoyant, walks in the woods became less zestful...
Page 55 - During the period of mood disturbance, three (or more) of the following symptoms have persisted (four if the mood is only irritable) and have been present to a significant degree: 1 . Inflated self-esteem or grandiosity 2.