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Teas, J., M.L. Harbison, and R.S. Gelman. 1984. Dietary seaweed (laminaria) and mammary carcinogenesis in rats. Cancer Res. 44:2758-2761.

Thomas, T.N., and J.W. Zemp. 1977. Inhibition of dopamine-sensitive adenylate cyclase from rat brain striatal homogenates by ascorbic acid. J. Neurochem. 28:663–665.

Tolbert, L.C., T.N. Thomas, L.D. Middaugh, and J.W. Zemp. 1979a. Ascorbate blocks amphetamine-induced turning behavior in rats with unilateral nigro-striatal lesions. Brain Res. Bull. 4:43-48.

Tolbert, L.C., T.N. Thomas, L.D. Middaugh, and J.W. Zemp. 1979b. Effect of ascorbic acid on neurochemical, behavioral, and physiological systems mediated by catecholamines. Life Sci. 25:2189-2195.

Tsao, C.S. 1991. Inhibiting effect of ascorbic acid on the growth of human mammary tumor xenografts. Am. J. Clin. Nutr. 54:1274S-1280S.

Turner, M. 1990. Garlic and circulatory disorders. J. R. Social Health 110(3):90–93.

U.S. Bureau of the Census. 1986. Statistical Abstract of the United States: 1986. U.S. Government Printing Office, Washington, D.C.

U.S. Department of Agriculture, Human Nutrition Information Service. 1988. Nationwide Food Consumption Survey, Continuing Survey of Food Intakes by Individuals. Women 19-50 and Their Children 1-5 Years, 4 Days (NFCS, CSFII 86-3). Washington, D.C.

U.S. Department of Agriculture. 1993a. Food Assistance Programs.

U.S. Department of Agriculture. 1993b. USDA News. Espy launches fresh start for school meals program. Release No. C749.93. Washington, D.C. September.

U.S. Department of Agriculture and U.S. Department of Health and Human Services. 1990. Nutrition and Your Health: Dietary Guidelines for Americans (3rd ed.). U.S. Government Printing Office, Washington, D.C.

U.S. Department of Education, National Center for Educational Statistics. 1990. Digest of Educational Statistics (NCES 91-660).

U.S. Department of Health and Human Services. 1987. Unproven Methods: The Gerson Therapy. National Cancer Institute statement, February 5.

U.S. Food and Drug Administration. 1992. Dietary Supplements Task Force-Final Report. National Technical Information Service, U.S. Department of Commerce, Springfield, Va.

Unsigned Commentary. 1994. Teething problems for two innovations. Science 264:1540.

Vaddadi, K.S., P. Courtney, C.J. Gilleard, M.S. Manku, and D.F. Horrobin. 1989. A double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia. Psychiatry Res. 27:313–323.

Valenzuela, G.J., and L.A. Munson. 1987. Magnesium and pregnancy. Magnesium 6:128–135.

Varga, J., S.A. Jimenez, and J. Uitto. 1993. L-tryptophan and the eosinophilia-myalgia syndrome: current understanding of the etiology and pathogenesis. J. Invest. Dermatol. 100(1):97S-105S.

Vartiainnen, E., H. Korhonen, P. Pietinen, et al. 1991. Fifteen-year trends in coronary risk factors in Finland, with special reference to North Karelia. Int. J. Epidemiol. 20(3):651-662.

Vega, G.L., and S.M. Grundy. 1994. Lipoprotein responses to treatment with lovastatin, gemfibrozil, and nicotinic acid in normolipidemic patients with hypoalphalipoproteinemia. Arch. Intern. Med. 154(1):73-82.

Vink, R. 1991-1992. Magnesium and brain trauma. Magnes. Trace Elem. 10:1-10.

Walford, R.L., and M. Crew. 1989. How dietary restriction retards aging: an integrative hypothesis. Growth Develop. Aging 53:139–140.

Walford, R.L., S.B. Harris, and M.W. Gunion. 1992. The calorically restricted, low-fat, nutrient-dense diet in Biosphere 2 significantly lowers blood glucose, total leukocyte count, cholesterol, and blood pressure in humans. Proc. Natl. Acad. Sci. U. S. A. 89:11533-11537.

Walsh, B.A. 1992. Urostomy and urinary pH. J. ET. Nurs. 19(4):110-113.

Walsh, D.C., R.E. Rudd, B.A. Moeykens, and T.W. Moloney. 1993. Social marketing for public health. Health Aff. 12(2):104-119.

Walter, H.J., A. Hofman, R.D. Vaughan, and F.L. Wynder. 1988. Modification of risk factors for coronary heart disease: five-year results of a school-based intervention trial. N. Engl. J. Med. 318:1093-1100.

Ward, P.S. 1988. History of Gerson Therapy. A contract report for the U.S. Congress Office of Technology Assessment. Revised June 1988.

Watson, K.V., C.F. Moldow, P.L. Ogburn, and H.S. Jacob. 1986. Magnesium sulfate: rationale for its use in preeclampsia. Proc. Natl. Acad. Sci. U. S. A. 83:1075-1078. Watts, G.F., B. Lewis, J.N.H. Brunt, et al. 1992. Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St. Thomas' Artherosclerosis Regression Study (STARS). Lancet 339:563-569.

Weaver, K. 1986. Pregnancy-induced hypertension and low birth weight in magnesium-deficient ewes. Magnesium 5:191-200.

Weaver, K. 1988. Magnesium and fetal growth. Tr. Subst. in Environmental Med. 22:136–142.

Weaver, K. 1990. Magnesium and migraine. Headache 30:168.

Wechsler, H., S. Levine, R.K. Idelson, M. Rohman, and J.O. Taylor. 1983. The physician's role in health promotion: a survey of primary-care practitioners. N. Engl. J. Med. 308:97-100.

Weglicki, W.B., A.M. Freedman, S. Bloom, et al. 1992. Antioxidants and the cardiomyopathy of Mg deficiency. Am. J. Cardiovasc. Pathol. 4:210–215.

Weglicki, W.B., R.E. Stafford, A.M. Freedman, M.M. Cassidy, and T.M. Phillips. 1993. Modulation of cytokines and myocardial lesions by vitamin E and chloroquine in a Mg-deficient rat model. Am. J. Physiol. 264:C723-C726.

Weinberg, E.D. 1992. Roles of iron in neoplasia: promotion, prevention, and therapy. Biol. Trace Elem. Res. 34(2):123-140.

Weisburger, J.H. 1993. Guest editorial: a new nutritional approach in cancer therapy in light of mechanistic understanding of cancer causation and development. J. Am. Coll. Nutr. 12:205-208.

Welsh, S., and J.F. Guthrie. 1991. The Changing American diets. In: A. Bendich and C. Butterworth, eds. Preventive Nutrition: The Role of Micronutrients in Health and Disease. Marcel Dekker: New York.

West, K.M. 1974. Diabetes in American Indians and other native populations of the New World. Diabetes 23(10):841-855.

Wigmore, A. 1985. Why Suffer? Avery Publishing, Wayne, N.J.

Wigmore, A. 1993. Scientific Appraisal of Dr. Ann Wigmore's Living Foods Lifestyle. Ann Wigmore Press, Boston. Willett, W.C. 1990. Nutritional Epidemiology. Oxford University Press, New York.

Willett, W.C. 1992. Folic acid and neural tube defect: can't we come to closure? Am. J. Public Health 82:666–668. Willett, W.C., and A. Ascherio. 1994. Trans fatty acids: are the effects only marginal? Am. J. Public Health 84(5):722724.

Willett, W.C., M.J. Stampfer, G.A. Colditz, B.A. Rosner, and F.E. Speizer. 1990. Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N. Engl. J. Med. 323:1664-1672.

Wilson, M.G., and E.W. Parry. 1954. Alpha-tocopherol in the prophylaxis of thromboembolism. Lancet 1:486-488. Windsor, R.A., and J.B. Lowe. 1989. Behavioral impact and cost analysis of a worksite self-help smoking cessation program. Prog. Clin. Biol. Res. 293:231-242.

Woods, K.L., and S. Fletcher. 1994. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2). Lancet 343:816-819.

Woods, K.L., S. Fletcher, C. Roffe, and Y. Haider. 1992. Intravenous magnesium sulphate in suspected acute myocardial infarction: results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2). Lancet 339:1553-1558.

World Health Organization. 1990. Diet, Nutrition, and the Prevention of Chronic Diseases: Report of a WHO Study Group (World Health Organization Technical Report Series 979). WHO, Geneva.

Yamamoto, I., H. Maruyama, and M. Moriguchi. 1987. The effect of dietary seaweeds on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats. Cancer Lett. 35:109–118.

Yoder, D. 1981. The sausage culture of the Pennsylvania Germans. In A. Fenton and R. Owen, eds. Food in Perspective. John Donald, Edinburgh.

Zhang, M.J., Q.F. Wang, L.X. Gao, H. Jin, and Z.Y. Wang. 1992. Comparative observation of the changes in serum lipid peroxides influenced by the supplementation of vitamin E in burn patients and healthy controls. Burns 18(1):19-21.

Zhao, X.Q., B.G. Brown, L. Hillger, et al. 1993. Effects of intensive lipid-lowering therapy on the coronary arteries of asymptomatic subjects with elevated apolipoprotein B. Circulation 88(6):2744–2753.

Ziegler, R.G. 1991. Vegetables, fruits, and carotenoids and the risk of cancer. Am. J. Clin. Nutr. 53(1 Suppl.):251S259S.

Zuspan, F.P., and M.C. Ward. 1965. Improved fetal salvage in eclampsia. Obstet. Gynecol. 26:893-897.

Part II

Conducting and Disseminating Research

Introduction

This part of the report discusses issues that confront all the alternative medical systems and practices, particularly those whose efficacy is under investigation. Although alternative medicine does not differ from mainstream medicine in the need for reasonable, responsible research and validation of safety and effectiveness, there are some issues unique to this branch of medicine:

• Lack of dedicated alternative medical research facilities.

• Lack of adequate funding for alternative medical research.

• Lack of training for alternative medical researchers.

• Lack of an adequate, centrally located research database.

• Difficulties in matching appropriate research methods to subjects being researched.

• Difficulties in obtaining appropriate National Institutes of Health (NIH) peer review of alternative medical grant applications.

• Difficulties in data collection related to various legal and regulatory constraints.

Consumers and clinicians have a definite and immediate need for access to the best and latest information about alternative medical practices, and NIH needs to be able to hear from health care consumers about their experiences with alternative practices.

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