Teratology in the Twentieth Century: Congenital Malformations in Humans and How their Environmental Causes were EstablishedElsevier, 2003 M06 6 - 166 pages This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment. |
From inside the book
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Page 132
... teratogenic mechanism 170 Dose- and time-response relations 170 Animal studies with thalidomide 171 Postscript: was anyone to blame? 172 The future? 172 TESTING FOR TERATOGENICITY Proposals for drug testing 173 The procedure 174 The ...
... teratogenic mechanism 170 Dose- and time-response relations 170 Animal studies with thalidomide 171 Postscript: was anyone to blame? 172 The future? 172 TESTING FOR TERATOGENICITY Proposals for drug testing 173 The procedure 174 The ...
Page 133
... teratogen 197 Endemic goiter 197 Organic mercury The Minamata epidemic 199 Congenital Minamata disease 199 Source of ... teratogenic? 217 Epilepsy and spontaneous abortion 217 Major congenital malformations 218 Carbamazepine 218 Valproic ...
... teratogen 197 Endemic goiter 197 Organic mercury The Minamata epidemic 199 Congenital Minamata disease 199 Source of ... teratogenic? 217 Epilepsy and spontaneous abortion 217 Major congenital malformations 218 Carbamazepine 218 Valproic ...
Page 139
... teratogenic danger signals.' 3. Classification 3.1. Introduction Almost as important as the necessity of defining ... teratogens (i.e., malformation-causing entities) such as ionizing radiation, the rubella virus, aminopterin, and ...
... teratogenic danger signals.' 3. Classification 3.1. Introduction Almost as important as the necessity of defining ... teratogens (i.e., malformation-causing entities) such as ionizing radiation, the rubella virus, aminopterin, and ...
Page 140
... teratogens and the multitude of single genes that are daily revealed to be responsible for prenatal mishaps is for the future to unveil. A possible reason for this poverty of etiological understanding is the relatively limited final ...
... teratogens and the multitude of single genes that are daily revealed to be responsible for prenatal mishaps is for the future to unveil. A possible reason for this poverty of etiological understanding is the relatively limited final ...
Page 141
... teratogenesis (discussed below), the effects on development of the fetal palate by different toxicants (Daston, 1993), give a faint picture of the ideas that may be brought into play in the search for mechanism.' What is considered here ...
... teratogenesis (discussed below), the effects on development of the fetal palate by different toxicants (Daston, 1993), give a faint picture of the ideas that may be brought into play in the search for mechanism.' What is considered here ...
Contents
CHAPTER 12 SURVEILLANCE OF CONGENITAL MALFORMATIONS | 181 |
CHAPTER 13 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS | 182 |
CHAPTER 14 HUMAN DISEASE AS TERATOGEN | 185 |
CHAPTER 15 ENVIRONMENTAL HAZARDS AND DISASTERS | 197 |
CHAPTER 16 DISEASE MEDICATION AND TERATOGENESIS | 210 |
CHAPTER 17 FOLIC ACID AND HUMAN MALFORMATIONS | 224 |
CHAPTER 18 ALCOHOL CONSUMPTION DURING PREGNANCY | 237 |
CHAPTER 19 THE ACCOMPLISHMENT AND THE EXPECTATION | 255 |
167 | |
CHAPTER 10 TESTING FOR TERATOGENICITY | 173 |
CHAPTER 11 TERATOLOGICAL DETOURS | 175 |
BIBLIOGRAPHY | 256 |
INDEX | 283 |
Other editions - View all
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Limited preview - 2003 |
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter No preview available - 2003 |
Common terms and phrases
abnormalities abortion agents alcohol animals anomalies appeared associated birth birth defects cause Child cleft congenital malformations considered consumption death defects deficiency diabetic discussed disease dose drinking drug early editors effects embryos environmental especially et al evidence examined experimental exposed exposure fact factors fetal findings folic acid frequency Genet given growth Health hospital human important included increased indicated induced infants Kalter known Lancet later less levels Love Canal major maternal means mental minor mothers neural tube neural tube defects normal noted occurred offspring origin outcome pattern Pediatr perhaps period population possible pregnancy prenatal present prevalence prospective question records reduced relation relatively reported retardation risk rubella seems severe specific spina bifida supplementation syndrome teratogenic Teratology testing thalidomide tion usually various vitamin Warkany weeks women York