Teratology in the Twentieth Century: Congenital Malformations in Humans and How their Environmental Causes were EstablishedElsevier, 2003 M06 6 - 166 pages This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment. |
From inside the book
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Page 133
... Risk assessment 211 Synthetic retinoids 212 Introduction: vitamin A toxicity 212 Isotretinoin 212 The population at risk 212 The retinoic acid embryopathy 213 Species dosage differences 213 Further teratologic threat: etretinate 213 ...
... Risk assessment 211 Synthetic retinoids 212 Introduction: vitamin A toxicity 212 Isotretinoin 212 The population at risk 212 The retinoic acid embryopathy 213 Species dosage differences 213 Further teratologic threat: etretinate 213 ...
Page 134
... risk 237 18. ALCOHOL CONSUMPTION DURING PREGNANCY Introduction: blessing and curse 237 Early Seattle study 237 Fetal alcohol syndrome 237 FAS expanded 238 FAS specificity 238 Diagnosing the FAS 239 Fetal alcohol effects 239 The ...
... risk 237 18. ALCOHOL CONSUMPTION DURING PREGNANCY Introduction: blessing and curse 237 Early Seattle study 237 Fetal alcohol syndrome 237 FAS expanded 238 FAS specificity 238 Diagnosing the FAS 239 Fetal alcohol effects 239 The ...
Page 146
... risk potential. But there are many others as well. 4.9. Underestimating frequency Systematic underestimation occurs when, e.g., investigative protocols are limited to newborn or even surviving newborn infants, i.e., that omit SABs and ...
... risk potential. But there are many others as well. 4.9. Underestimating frequency Systematic underestimation occurs when, e.g., investigative protocols are limited to newborn or even surviving newborn infants, i.e., that omit SABs and ...
Page 154
... risk component—contrary to its usual importance in nonviral teratogenesis—appears not to be involved: the intensity of the maternal disease did not seem to be related to the type, severity, or frequency of the malformations produced ...
... risk component—contrary to its usual importance in nonviral teratogenesis—appears not to be involved: the intensity of the maternal disease did not seem to be related to the type, severity, or frequency of the malformations produced ...
Page 155
... risk frequencies appear to be, they were based on 102 offspring, only 20 of whom were defective, a relatively low frequency, undoubtedly due to 54% of the infected women having been therapeutically aborted, mostly in the earliest weeks ...
... risk frequencies appear to be, they were based on 102 offspring, only 20 of whom were defective, a relatively low frequency, undoubtedly due to 54% of the infected women having been therapeutically aborted, mostly in the earliest weeks ...
Contents
135 | |
136 | |
139 | |
143 | |
148 | |
CHAPTER 6 PIONEERING WORKS | 157 |
CHAPTER 7 EARLY EXPERIMENTS | 159 |
CHAPTER 8 NEW CHALLENGES | 166 |
CHAPTER 12 SURVEILLANCE OF CONGENITAL MALFORMATIONS | 181 |
CHAPTER 13 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS | 182 |
CHAPTER 14 HUMAN DISEASE AS TERATOGEN | 185 |
CHAPTER 15 ENVIRONMENTAL HAZARDS AND DISASTERS | 197 |
CHAPTER 16 DISEASE MEDICATION AND TERATOGENESIS | 210 |
CHAPTER 17 FOLIC ACID AND HUMAN MALFORMATIONS | 224 |
CHAPTER 18 ALCOHOL CONSUMPTION DURING PREGNANCY | 237 |
CHAPTER 19 THE ACCOMPLISHMENT AND THE EXPECTATION | 255 |
CHAPTER 9 THALIDOMIDE | 167 |
CHAPTER 10 TESTING FOR TERATOGENICITY | 173 |
CHAPTER 11 TERATOLOGICAL DETOURS | 175 |
BIBLIOGRAPHY | 256 |
INDEX | 283 |
Other editions - View all
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Limited preview - 2003 |
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter No preview available - 2003 |
Common terms and phrases
abnormalities abortion agents alcohol animals anomalies appeared associated birth birth defects cause Child cleft congenital malformations considered consumption death defects deficiency diabetic discussed disease dose drinking drug early editors effects embryos environmental especially et al evidence examined experimental exposed exposure fact factors fetal findings folic acid frequency Genet given growth Health hospital human important included increased indicated induced infants Kalter known Lancet later less levels Love Canal major maternal means mental minor mothers neural tube neural tube defects normal noted occurred offspring origin outcome pattern Pediatr perhaps period population possible pregnancy prenatal present prevalence prospective question records reduced relation relatively reported retardation risk rubella seems severe specific spina bifida supplementation syndrome teratogenic Teratology testing thalidomide tion usually various vitamin Warkany weeks women York