Teratology in the Twentieth Century: Congenital Malformations in Humans and How their Environmental Causes were EstablishedElsevier, 2003 M06 6 - 166 pages This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment. |
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Page 132
... Induced and spontaneous malformations 164 Genetics and individual responses 164 The multifactorial/threshold concept 164 A new concept of embryotoxicity 165 A variety of experiments 165 Vitamin antimetabolites 165 Folic acid 166 Folic ...
... Induced and spontaneous malformations 164 Genetics and individual responses 164 The multifactorial/threshold concept 164 A new concept of embryotoxicity 165 A variety of experiments 165 Vitamin antimetabolites 165 Folic acid 166 Folic ...
Page 136
... induce malformations in laboratory animals (Hippel, 1907). These strands, destined to become intimately entwined, epitomize the dichotomy-heredity and environment—in the foremost quest in modern teratology, the search for the causes of ...
... induce malformations in laboratory animals (Hippel, 1907). These strands, destined to become intimately entwined, epitomize the dichotomy-heredity and environment—in the foremost quest in modern teratology, the search for the causes of ...
Page 139
... induced, and somatic mutations, and—bewilderingly—overripeness of the egg, and in the latter, H. Kalter / Neurotoxicology and Teratology 25 (2003) 131–282 139 Minor malformations and variants CHAPTER 3. CLASSIFICATION Introduction: why ...
... induced, and somatic mutations, and—bewilderingly—overripeness of the egg, and in the latter, H. Kalter / Neurotoxicology and Teratology 25 (2003) 131–282 139 Minor malformations and variants CHAPTER 3. CLASSIFICATION Introduction: why ...
Page 148
... induced congenital malformations were made in animals and humans. Those in animals were the first ventures into the area of experimental mammalian teratology. 5.2. X-irradiation 5.2.1. Introduction: animal studies Teratologic ...
... induced congenital malformations were made in animals and humans. Those in animals were the first ventures into the area of experimental mammalian teratology. 5.2. X-irradiation 5.2.1. Introduction: animal studies Teratologic ...
Page 149
... induced congenital malformation in human beings. An important point remained: to learn whether there was a period during prenatal life that was most sensitive to the irradiation. Reexamining the data, the investigators found the answer ...
... induced congenital malformation in human beings. An important point remained: to learn whether there was a period during prenatal life that was most sensitive to the irradiation. Reexamining the data, the investigators found the answer ...
Contents
CHAPTER 12 SURVEILLANCE OF CONGENITAL MALFORMATIONS | 181 |
CHAPTER 13 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS | 182 |
CHAPTER 14 HUMAN DISEASE AS TERATOGEN | 185 |
CHAPTER 15 ENVIRONMENTAL HAZARDS AND DISASTERS | 197 |
CHAPTER 16 DISEASE MEDICATION AND TERATOGENESIS | 210 |
CHAPTER 17 FOLIC ACID AND HUMAN MALFORMATIONS | 224 |
CHAPTER 18 ALCOHOL CONSUMPTION DURING PREGNANCY | 237 |
CHAPTER 19 THE ACCOMPLISHMENT AND THE EXPECTATION | 255 |
167 | |
CHAPTER 10 TESTING FOR TERATOGENICITY | 173 |
CHAPTER 11 TERATOLOGICAL DETOURS | 175 |
BIBLIOGRAPHY | 256 |
INDEX | 283 |
Other editions - View all
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Limited preview - 2003 |
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter No preview available - 2003 |
Common terms and phrases
abnormalities abortion agents alcohol animals anomalies appeared associated birth birth defects cause Child cleft congenital malformations considered consumption death defects deficiency diabetic discussed disease dose drinking drug early editors effects embryos environmental especially et al evidence examined experimental exposed exposure fact factors fetal findings folic acid frequency Genet given growth Health hospital human important included increased indicated induced infants Kalter known Lancet later less levels Love Canal major maternal means mental minor mothers neural tube neural tube defects normal noted occurred offspring origin outcome pattern Pediatr perhaps period population possible pregnancy prenatal present prevalence prospective question records reduced relation relatively reported retardation risk rubella seems severe specific spina bifida supplementation syndrome teratogenic Teratology testing thalidomide tion usually various vitamin Warkany weeks women York