Teratology in the Twentieth Century: Congenital Malformations in Humans and How their Environmental Causes were EstablishedThis book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment. |
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Page 132
... monitoring 181 Monitoring's limited abilities 182 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS The classical method 182 Epidemiology of malformation communities 183 Familial studies 183 Pyloric stenosis 183 Clefts of the lip and palate ...
... monitoring 181 Monitoring's limited abilities 182 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS The classical method 182 Epidemiology of malformation communities 183 Familial studies 183 Pyloric stenosis 183 Clefts of the lip and palate ...
Page 136
... vast pedigrees were gathered of families containing members with such abnormalities, e.g., in addition to those mentioned, symphalangism, polydactylism, harelip (as cleft lip was long known), cleft palate, etc., some of the most ...
... vast pedigrees were gathered of families containing members with such abnormalities, e.g., in addition to those mentioned, symphalangism, polydactylism, harelip (as cleft lip was long known), cleft palate, etc., some of the most ...
Page 147
Examples are an excess of a mild type of polydactyly in blacks (e.g., Altemus and Ferguson, 1965; Christianson et al., 1981) and of orofacial clefts in Japanese and some North American Indians (Tanaka, 1963; Lowry and Trimble, 1977), ...
Examples are an excess of a mild type of polydactyly in blacks (e.g., Altemus and Ferguson, 1965; Christianson et al., 1981) and of orofacial clefts in Japanese and some North American Indians (Tanaka, 1963; Lowry and Trimble, 1977), ...
Page 149
... the embryonic optic cleft persisted and the iris and ciliary processes were rudimentary. Although the eyes were of size appropriate for the fetal age, the authors commented that “the possibility of microphthalmia, had the embryo ...
... the embryonic optic cleft persisted and the iris and ciliary processes were rudimentary. Although the eyes were of size appropriate for the fetal age, the authors commented that “the possibility of microphthalmia, had the embryo ...
Page 157
This first report was soon followed by others of more extensive and better controlled experiments (Hale, 1935, 1937), which reproduced the ophthalmic defects, and noted that other types of malformations also occurred, cleft lip, ...
This first report was soon followed by others of more extensive and better controlled experiments (Hale, 1935, 1937), which reproduced the ophthalmic defects, and noted that other types of malformations also occurred, cleft lip, ...
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Contents
CHAPTER 12 SURVEILLANCE OF CONGENITAL MALFORMATIONS | 181 |
CHAPTER 13 EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS | 182 |
CHAPTER 14 HUMAN DISEASE AS TERATOGEN | 185 |
CHAPTER 15 ENVIRONMENTAL HAZARDS AND DISASTERS | 197 |
CHAPTER 16 DISEASE MEDICATION AND TERATOGENESIS | 210 |
CHAPTER 17 FOLIC ACID AND HUMAN MALFORMATIONS | 224 |
CHAPTER 18 ALCOHOL CONSUMPTION DURING PREGNANCY | 237 |
CHAPTER 19 THE ACCOMPLISHMENT AND THE EXPECTATION | 255 |
| 167 | |
CHAPTER 10 TESTING FOR TERATOGENICITY | 173 |
CHAPTER 11 TERATOLOGICAL DETOURS | 175 |
BIBLIOGRAPHY | 256 |
INDEX | 283 |
Other editions - View all
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter Limited preview - 2003 |
Teratology in the Twentieth Century: Congenital Malformations in Humans and ... H. Kalter No preview available - 2003 |
Common terms and phrases
abnormalities abortion agents alcohol animals anomalies appeared associated birth birth defects cause Child cleft congenital malformations considered consumption death defects deficiency diabetic discussed disease dose drinking drug early editors effects embryos environmental especially et al evidence examined experimental exposed exposure fact factors fetal findings folic acid frequency Genet given growth Health hospital human important included increased indicated induced infants Kalter known Lancet later less levels Love Canal major maternal means mental minor mothers neural tube neural tube defects normal noted occurred offspring origin outcome pattern Pediatr perhaps period population possible pregnancy prenatal present prevalence prospective question records reduced relation relatively reported retardation risk rubella seems severe specific spina bifida supplementation syndrome teratogenic Teratology testing thalidomide tion usually various vitamin Warkany weeks women York