Biochemistry of Vitamin AThe main emphasis of this text is on the biochemistry, metabolism and systemic mode of action of vitamin A. The physiological, biochemical and nutritional aspects of naturally occurring retinoids are clearly addressed. Chapters review biogenesis, absorption, storage, transport, and metabolic transformations of vitamin A. Further discussion includes vision and bacteriorhodopsin, vitamin A deficiency and hypervitaminosis A, and the vitamin A in prevention and cure of cancer. |
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Contents
Chapter | 1 |
References | 15 |
Carboxylic Esterases | 21 |
Dehydrogenation of Retinol to Retinaldehyde | 32 |
Chapter 3 | 41 |
References | 49 |
Types of Cells | 55 |
Chapter 5 | 63 |
On the Question of an Active Form of Vitamin A | 109 |
Systemic Mode of Action | 115 |
Effect of Vitamin A Deprivation on the General Physiology | 121 |
Binding of Retinol with Chromatin | 135 |
Vision and Bacteriorhodopsin | 145 |
CRALBP | 153 |
Bacteriorhodopsin | 159 |
Chapter 10 | 165 |
Chapter 9 | 66 |
Tissue Distribution | 68 |
References | 80 |
Effect of Hormones on CRABP Levels in Rats | 92 |
Chapter 7 | 101 |
Vitamin A Deficiency | 172 |
References | 193 |
Dermatology | 203 |
Appendix | 209 |
Common terms and phrases
absorption acetate activity actual amounts animals appeared B-carotene bile binding protein Biochem Biol Biophys blood carotene carotenoids cells cellular changes Chem cholesterol chromatography compared complex compounds concentrations conclusively containing contents CRBP culture deficiency demonstrated diet differentiation dose effects effects of vitamin enzyme epithelium esterification et al experiments extensive fatty acids Figure fraction functions further Ganguly given glycosyl Goodman growth human identified increase incubated injection intestine isolated keratin labeled later levels Lipid membrane metabolism metabolites molecular weight molecule normal Nutr observed organ palmitate plasma preparation present purified radioactivity rat liver reaction recent reported retinaldehyde retinoic acid retinoids retinol retinol-binding protein retinyl esters revealed seen serum showed shown significant similar Smith specific studies suggested supplementation synthesis Table testes tissues transport values various vitamin A deprivation vitamin A-deficient rats whereas workers
Popular passages
Page 206 - Willett WC, Polk BF, Underwood BA, et al. Relation of serum vitamins A and E and carotenoids to the risk of cancer.