ACCELERATOR DESIGN SOFTWARE Because of the recent interest in the utilization of synchrotron radiation sources for commercial x-ray lithography, several firms have requested and obtained copies of the LBL accelerator physics code ZAP. The code is useful in designing such machines and assessing their performance. In the past year, the code was sent to two Japanese firms (Ishikawajima-Harima Heavy Industries and Mitsubishi Electric Company) and to IBM in New York. In addition, the code was provided to the Synchrotron Trieste Company, a consortium of Italian business and government organizations assembled to build a synchrotron radiation source in Trieste, Italy. Several scientists from the Accelerator and Fusion Research Division visited Trieste this summer to provide instructions on the use of ZAP and to participate in the training of the staff there for the design effort that is just beginning. An H ion source using the so-called volume-production process was fabricated for the Grumman Corporation, which had requested the source in connection with SDI-related R&D activity. Transfer of this technology was based on expertise acquired during source development work for the magnetic fusion program. DOE - Lawrence Berkeley Laboratory VIDEO MOVIE SYSTEM FOR THE DISPLAY OF SCIENTIFIC DATA A versatile, low cost video movie making system has been developed at the Lawrence Berkeley Laboratory for making movie-like displays of time dependent data by suing single frame animation techniques. This system consists of a PC microcomputer based animation controller, a video frame buffer, and a 1/2" editing video tape recorder and is designed to function as a remote device from where the numerical simulation is being The remote application can access the display system directly by using remote procedure calls or by sending data files containing representations of graphics to the device for later processing on to video tape. This system has been used by a number of LBL scientists for displaying the results of time dependent numerical simulations. run. Over fifteen requests for detailed plans for building this device have been made. These requests came from a number of universities, research laboratories, and industry. Several of these organizations have replicated the system and one commercial organization is designing a product based on this technology. DOE - Lawrence Berkeley Laboratory HUMAN MAMMARY EPITHELIAL CELLS Human mammary epithelial cell strains derived from normal and malignant tissues, and cell lines derived from normal cells transformed to immortality after exposure in vitro to benzo(a)pyrene, have been provided to numerous investigators and biotechnology companies. These cells are being used to study normal and abnormal human cell physiology and biochemistry, immunology, growth factor and oncogene action, genetics, and mechanisms of carcinogenesis. Companies currently using these cells include: Cetus Corporation, Eli Lilly, Hybridtech Inc., and Syntex Research. Academic and research organizations using these cells include: Academy of Science (DDR), Baylor College of Medicine, Children's Hospital-Oakland, Dana-Farber Cancer Institute, Dutch Cancer Institute, Imperial Cancer Research Fund, INSERSM, National Cancer Institute, Peralta Cancer Research Institute, U. Arkansas, U. California, U. Colorado, U. Southern California, U. Wisconsin, and Veterans Hospital in New York. DOE - Lawrence Berkeley Laboratory BIOGLASS APPLICATION FOR HELPING DIABETICS In the first meeting of the SDIO Bio-Medical Applications panel, it was determined that new Bioglass material promises a dramatic improvement with another new bio-medical innovation - the Programmable Implantable Medication System (PIMS) which itself uses satellite telemetry technology and NASA Mars Viking Lander technology to automatically dispense insulin for diabetics. The inventor of the PIMS, Mr. Fischell of Johns Hopkins University Applied Physics Laboratory is a member of the SDIO Bio-Medical Technology Applications Panel. DOD - Strategic Defense Initiatives Organization SAFER METHODS FOR FOOD PRESERVATION The Department of Energy is currently negotiation an agreement with the Lawrence Livermore National Laboratory to use the Linear Accelerator technology developed under the SDI Program as the principal source for implementing a large scale food irradiation program. The program will be initially implemented in six states (Hawaii, Alaska, Oklahoma, Florida, Washington, and New Jersey). This technology provides a much safer (non-nuclear) source to irradiate food so that meats, fruits, and vegetables can be stored for prolonged periods without spoilage. DOD - Strategic Defense Initiatives Organization NEUTRAL PARTICLE BEAM (NPB) MEDICAL AND INDUSTRIAL SPINOFFS Linear Accelerator technology developed in response to SDI requirements for a source for neutral particle beam technology at Los Alamos National Laboratory has lent itself to spinoff applications for both Medical and industrial applications. The key element of the technology is a Radio Frequency Quadripole linear accelerator, known as an "RFQ" Linac. Originally a Russian concept proposed in 1970, the first RFQ was tested at Los Alamos in 1980. Competition efforts on Neutral Particle Beam requirements led to the invention of the "precision segment" RFQ Linac by Boeing and AccSys Technology Incorporated which produced the base line design for the initial stage of the accelerator in the SDI Neutral Particle Beam Integrated Space Experiment. Related supporting technologies (ion injector, rf power source, vacuum pumping system, water cooling system, mechanical structures, instrumentation and controls) have also been pushed by NPB requirements resulting in smaller, lighter, rugged, more efficient and reliable and reliable systems. Actual and projected applications of this technology follow: PRODUCTION OF RADIOISOTOPES FOR MEDICAL DIAGNOSIS The RFQ design has now been incorporated into a compact proton linac to produce medical radioisotopes for Positron Emission Tomagraphy via a SBIR frant from the National Cancer Institute. These isotopes are principally used in study and diagnosis of brain and heart disease. The new technology has produced a smaller, lighter (easier to shield), less complex, more energy efficient and safer source than other methods. Commercial production is expected by 1989. Additional medical needs are being assessed for other radionscopes created by this new technology. CANCER THERAPY APPLICATIONS Loma Linda University hospital in southern California has selected the SDI derived RFQ Linac device for use in their ion therapy cancer treatment facility now under construction. It is anticipated that three to five more facilities will be built using this technology over the next five to ten years. SEMICONDUCTOR MANUFACTURE ENHANCEMENTS Applications of the NPB RFQ Linac technology into an ion implantation device which will be used for doping semiconductor materials with high energy ions of boron, phosphorus and arsenic is being designed. Manufacturing devices will be built at users facilities under license agreements. OIL WELL LOGGING AND MINERAL SURVEYS The RFQ Linac's compact size lends itself to applications in the fabrication of survey tools for Oil well logging operations where it can be used in a well shaft without the danger of contaminating an oil field with a dropped radioisotope inherent with the current procedure. The instrumentation could also be used to assay mineral content in mining operations. DOD - Strategic Defense Initiatives Organization NEW INSTRUMENTATION FOR ENTOMOLOGISTS The Laser Doppler Radar technology developed under SDI contract at Oak Ridge National Laboratory has been packaged into a small prototype device which can be used to detect and discriminate the presence of various species of insects. This new device could provide an entirely new and more effective analysis tool for entomologists. This device is useful in detecting the presence of a queen bee in hives, the presence of various species of harmful insects, and particularly valuable in identifying the African "Killer Bee". The U.S. and Mexican Departments of Agriculture are currently working with the inventor regarding applications of this technology. A potential application for both the Neutral Particle Beam associated RFQ linac work at LANL and Laser Doppler Radar Technology at Oak Ridge National Lab is the inspection and analysis of potentially dangerous bridge structures in the national highway system. The SDIO Office of Technology Applications is working with the Department of Transportation on these potential applications. |