Lopid Patent Term Restoration and Fairness Act of 1987: Hearing Before the Subcommittee on Courts, Civil Liberties, and the Administration of Justice of the Committee on the Judiciary, House of Representatives, One Hundredth Congress, First Session, October 8, 1987, Volume 4U.S. Government Printing Office, 1988 - 350 pages |
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Results 1-5 of 26
Page 62
... weeks ) . Results demonstrate that Lopid produced marked reduction in triglycerides in all studies . European ... week placebo washout . Enrollment involved 469 patients , average age , 54.6 years . Above study completed . All patient ...
... weeks ) . Results demonstrate that Lopid produced marked reduction in triglycerides in all studies . European ... week placebo washout . Enrollment involved 469 patients , average age , 54.6 years . Above study completed . All patient ...
Page 103
... week placebo - controlled study , gemfibrozil was given to 10 patients with evidence of severe atherosclerosis . Four similar patients acted as controls . In the treated group , total cholesterol and triglycerides decreased ...
... week placebo - controlled study , gemfibrozil was given to 10 patients with evidence of severe atherosclerosis . Four similar patients acted as controls . In the treated group , total cholesterol and triglycerides decreased ...
Page 104
... weeks on placebo , ten patients ( the treated group ) received gemfibrozil 1200 mg / day for 13 weeks . The four controls were given tablets identical in appearance but containing lactose . They provided blood samples according to the ...
... weeks on placebo , ten patients ( the treated group ) received gemfibrozil 1200 mg / day for 13 weeks . The four controls were given tablets identical in appearance but containing lactose . They provided blood samples according to the ...
Page 105
... Weeks on drug 13 8 13 per cent ) 380 +1.0 +0.3 +1.0 + 5 · 0 377 - 2.0 12.0 +5.0 -1.0 HTCT ( s ) 20 + 20 + 85 ** +75 ... week 1 but thereafter was markedly and significantly prolonged , i.e. less HNA was present . This test is difficult ...
... Weeks on drug 13 8 13 per cent ) 380 +1.0 +0.3 +1.0 + 5 · 0 377 - 2.0 12.0 +5.0 -1.0 HTCT ( s ) 20 + 20 + 85 ** +75 ... week 1 but thereafter was markedly and significantly prolonged , i.e. less HNA was present . This test is difficult ...
Page 107
... weeks . Plasma LDL - cholesterol decreased during the entire treatment period , by about 10 per cent at the end of the study , suggesting that 24 weeks of treatment may be insufficient to reveal the maximum extent of LDL - cholesterol ...
... weeks . Plasma LDL - cholesterol decreased during the entire treatment period , by about 10 per cent at the end of the study , suggesting that 24 weeks of treatment may be insufficient to reveal the maximum extent of LDL - cholesterol ...
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Common terms and phrases
apolipoprotein Association atherosclerosis baseline bill blood Capsules cardiovascular cent Chairman changes cholesterol cholesterol levels cholestyramine clofibrate Committee concentrations coronary heart disease decrease diabetic diet dose Drug Administration dyslipidaemic effect of gemfibrozil elevated fatty acid composition FDA approval Finland follow-up Food and Drug Framingham gemfibrozil treatment glucose HDL-cholesterol Health heart attacks Helsinki Heart Study hypercholesterolaemia hypertension incidence increase ischaemic heart disease Journal KASTENMEIER Kaukola laboratory legislation lipid lowering Lipid Research Clinics lipid-lowering lipoprotein cholesterol lipoprotein lipase lipoprotein lipase activity Lithell long-term Lopid Lopid patent low density lipoprotein LRC-CPPT male Manninen market exclusivity metabolism mmol/l mortality myocardial infarction Parke-Davis patent extension patent term extension patients pharmaceutical Phase IV study placebo Primary Prevention Trial ratio reduction regulatory risk factors Royal Society safety serum cholesterol serum lipid significant Society of Medicine Subcommittee Table Term Restoration Act therapy treatment groups triglycerides Vessby VLDL Warner-Lambert Waxman-Hatch
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