Lopid Patent Term Restoration and Fairness Act of 1987: Hearing Before the Subcommittee on Courts, Civil Liberties, and the Administration of Justice of the Committee on the Judiciary, House of Representatives, One Hundredth Congress, First Session, October 8, 1987, Volume 4U.S. Government Printing Office, 1988 - 350 pages |
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Page 93
... et al . 1976 , Olsson et al . 1976 , Vessby et al . 1976 ) . However , information on the mechanisms by which gemfibrozil influences triglyceride metabolism in hypertriglyceridaemia is rather sparse . The present study was undertaken to ...
... et al . 1976 , Olsson et al . 1976 , Vessby et al . 1976 ) . However , information on the mechanisms by which gemfibrozil influences triglyceride metabolism in hypertriglyceridaemia is rather sparse . The present study was undertaken to ...
Page 94
... et al . the plasma lipid esters was also studied during and after treatment to investigate any possible changes ... et al . 1971 ) using a combination of preparative ultracentrifugation ( Havel et al . 1955 ) and heparin - manganese ...
... et al . the plasma lipid esters was also studied during and after treatment to investigate any possible changes ... et al . 1971 ) using a combination of preparative ultracentrifugation ( Havel et al . 1955 ) and heparin - manganese ...
Page 95
... all fatty acids together . Other fatty acids identified but present in concentrations no greater than 0.1 per cent are not reported on . A detailed description of the separation procedure has been reported elsewhere ( Boberg et al ...
... all fatty acids together . Other fatty acids identified but present in concentrations no greater than 0.1 per cent are not reported on . A detailed description of the separation procedure has been reported elsewhere ( Boberg et al ...
Page 96
... et al . Table 1 Serum lipoprotein and apolipoprotein concentrations during and after termination of gemfibrozil treatment ( mean ± SEM ; n = 17 ) After gemfibrozil VLDL TG , mmol / l VLDL CHOL , mmol / l LDL TG , mmol / l LDL CHOL ...
... et al . Table 1 Serum lipoprotein and apolipoprotein concentrations during and after termination of gemfibrozil treatment ( mean ± SEM ; n = 17 ) After gemfibrozil VLDL TG , mmol / l VLDL CHOL , mmol / l LDL TG , mmol / l LDL CHOL ...
Page 98
... et al . -20 -40 -30 -20 -10 O LIPOPROTEIN LIPASE ACTIVITY , mU / g 10 Figure 1. Relationship ( r = 0.86 ; p < 0.001 ) between changes of LDL - cholesterol and skeletal muscle lipoprotein lipase activity ( mU / g ) after cessation of ...
... et al . -20 -40 -30 -20 -10 O LIPOPROTEIN LIPASE ACTIVITY , mU / g 10 Figure 1. Relationship ( r = 0.86 ; p < 0.001 ) between changes of LDL - cholesterol and skeletal muscle lipoprotein lipase activity ( mU / g ) after cessation of ...
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apolipoprotein Association atherosclerosis baseline bill blood Capsules cardiovascular cent Chairman changes cholesterol cholesterol levels cholestyramine clofibrate Committee concentrations coronary heart disease decrease diabetic diet dose Drug Administration dyslipidaemic effect of gemfibrozil elevated fatty acid composition FDA approval Finland follow-up Food and Drug Framingham gemfibrozil treatment glucose HDL-cholesterol Health heart attacks Helsinki Heart Study hypercholesterolaemia hypertension incidence increase ischaemic heart disease Journal KASTENMEIER Kaukola laboratory legislation lipid lowering Lipid Research Clinics lipid-lowering lipoprotein cholesterol lipoprotein lipase lipoprotein lipase activity Lithell long-term Lopid Lopid patent low density lipoprotein LRC-CPPT male Manninen market exclusivity metabolism mmol/l mortality myocardial infarction Parke-Davis patent extension patent term extension patients pharmaceutical Phase IV study placebo Primary Prevention Trial ratio reduction regulatory risk factors Royal Society safety serum cholesterol serum lipid significant Society of Medicine Subcommittee Table Term Restoration Act therapy treatment groups triglycerides Vessby VLDL Warner-Lambert Waxman-Hatch
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