Lopid Patent Term Restoration and Fairness Act of 1987: Hearing Before the Subcommittee on Courts, Civil Liberties, and the Administration of Justice of the Committee on the Judiciary, House of Representatives, One Hundredth Congress, First Session, October 8, 1987, Volume 4U.S. Government Printing Office, 1988 - 350 pages |
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Page 90
... apolipoprotein A - I and A - Il concentrations in dyslipidaemic subjects 1 11 15 SIRKKA KAUKOLA , VESA MANNINEN , CHRISTIAN EHNHOLM and MARJATTA MÄLKÖNEN . 23 Augmentation of gemfibrozil - induced hypolipidaemia by psyllium- based fibre ...
... apolipoprotein A - I and A - Il concentrations in dyslipidaemic subjects 1 11 15 SIRKKA KAUKOLA , VESA MANNINEN , CHRISTIAN EHNHOLM and MARJATTA MÄLKÖNEN . 23 Augmentation of gemfibrozil - induced hypolipidaemia by psyllium- based fibre ...
Page 93
... apolipoprotein ( apo ) B concentration increased ( + 12 per cent ; p < 0.01 ) and apo A - 1 and apo A - II decreased by 6 per cent ( p < 0.05 ) and 11 per cent ( p < 0 · 05 ) respectively . Triglyceride reduction during gemfibrozil ...
... apolipoprotein ( apo ) B concentration increased ( + 12 per cent ; p < 0.01 ) and apo A - 1 and apo A - II decreased by 6 per cent ( p < 0.05 ) and 11 per cent ( p < 0 · 05 ) respectively . Triglyceride reduction during gemfibrozil ...
Page 94
... apolipoprotein ( apo ) A - I , A - II and B concentrations in serum were determined by electro - immunoassay according to the methods of Vessby et al . ( 1980a , b ) . Serum apolipoprotein concentrations are expressed as arbitrary units ...
... apolipoprotein ( apo ) A - I , A - II and B concentrations in serum were determined by electro - immunoassay according to the methods of Vessby et al . ( 1980a , b ) . Serum apolipoprotein concentrations are expressed as arbitrary units ...
Page 95
... apolipoprotein concentrations On terminating gemfibrozil treatment there were , as expected , significant increases of triglyceride concentrations in VLDL , LDL and HDL while HDL cholesterol decreased significantly , by an average of 21 ...
... apolipoprotein concentrations On terminating gemfibrozil treatment there were , as expected , significant increases of triglyceride concentrations in VLDL , LDL and HDL while HDL cholesterol decreased significantly , by an average of 21 ...
Page 96
... apolipoprotein concentrations during and after termination of gemfibrozil treatment ( mean ± SEM ; n = 17 ) After ... apolipoprotein . AU arbitrary units = lipids and apolipoproteins , the only differences were in LDL - cholesterol and ...
... apolipoprotein concentrations during and after termination of gemfibrozil treatment ( mean ± SEM ; n = 17 ) After ... apolipoprotein . AU arbitrary units = lipids and apolipoproteins , the only differences were in LDL - cholesterol and ...
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apolipoprotein Association atherosclerosis baseline bill blood Capsules cardiovascular cent Chairman changes cholesterol cholesterol levels cholestyramine clofibrate Committee concentrations coronary heart disease decrease diabetic diet dose Drug Administration dyslipidaemic effect of gemfibrozil elevated fatty acid composition FDA approval Finland follow-up Food and Drug Framingham gemfibrozil treatment glucose HDL-cholesterol Health heart attacks Helsinki Heart Study hypercholesterolaemia hypertension incidence increase ischaemic heart disease Journal KASTENMEIER Kaukola laboratory legislation lipid lowering Lipid Research Clinics lipid-lowering lipoprotein cholesterol lipoprotein lipase lipoprotein lipase activity Lithell long-term Lopid Lopid patent low density lipoprotein LRC-CPPT male Manninen market exclusivity metabolism mmol/l mortality myocardial infarction Parke-Davis patent extension patent term extension patients pharmaceutical Phase IV study placebo Primary Prevention Trial ratio reduction regulatory risk factors Royal Society safety serum cholesterol serum lipid significant Society of Medicine Subcommittee Table Term Restoration Act therapy treatment groups triglycerides Vessby VLDL Warner-Lambert Waxman-Hatch
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