Vascular Dementia: Cerebrovascular Mechanisms and Clinical Management

Front Cover
Robert H. Paul
Springer Science & Business Media, 2007 M11 17 - 372 pages
A multidisciplinary survey of our current understanding of the biological and clinical aspects of vascular disease. The authors describe its basic mechanisms, its clinical characteristics, its pharmacological management, and the use of neuroimaging methods to investigate it. The complex relationship between VaD and AD is also fully explored with chapters on how these processes interact and how one disease may lower the threshold for clinical expression of the other.
 

Contents

Clinical Forms of Vascular Dementia
7
The Neuropathological Substrates of VascularIschemic Dementia
23
Conceptual Challenges
57
Cerebral Hemodynamics in the Elderly
75
The CADASIL Syndrome and Other Genetic Causes
87
Estrogen the Cerebrovascular System and Dementia
99
Effects of Hypertension in Young Adult and MiddleAged Rhesus Monkeys
113
The Cognitive Profile of Vascular Dementia
131
The Role of Strategic Infarcts
231
Understanding Incidence and Prevalence Rates
245
Vascular Basement Membrane Abnormalities and Alzheimers Disease
257
Amyloid Beta and the Cerebral Vasculature
267
Cerebrovascular Disease and the Expression of Alzheimers Disease
275
The Neuropsychological Differentiation Between Alzheimers Disease
281
Pharmacological Treatment of Vascular Dementia
297
Understanding and Managing Caregiver Burden
305

Progression of Cognitive Impairments Associated
145
Functional Impairment in Vascular Dementia
171
Functional Brain Imaging of Cerebrovascular Disease
181
Contributions of Subcortical Lacunar Infarcts
211
White Matter Hyperintensities and Cognition
223
Quality of Life in Patients With Vascular Dementia
323
Approaches to Neuroprotection and Recovery Enhancement
331
Index
341
About the Editors
355
Copyright

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