List of research projects recommended to the American Cancer Society by the` committee on growth-Continued Panel on mutations: DIVISION OF BIOLOGY-Continued Investigator: Demerec, M., Ph. D. Institution: Carnegie Institution, department of genetics. Institution: California Institute of Technology. $750 Period of grant: Jan. 1, 1946, to June 30, 1946--- 2,250 Institution: University of Missouri, Columbia Title of project: "Position Effect or Gene Mutations Influenced by Changes in Gene Position and Gene Association in Drosophila Period of grant: Jan. 1, 1946, to June 30, 1946- 910 Title of project: "Mechanism of Synthesis and Maintenance of Period of grant: July 1, 1946, to June 30, 1947_ 1 3, 500 Investigator: Kimball, R. F., Ph. D. Institution: Johns Hopkins University. Title of project: "Production of Resistance to Antiserum Against Period of grant: March 1, 1946, to June 30, 1947. 2, 860 Investigator: Muller, H. J., Ph. D. Institution: Indiana University, Bloomington, Ind. Title of project: "The Proportion of Detectable Deficiencies on 900 Institution: Yale University. Title of project: "The Production of Mutant Strains of Neurospora 750 Title of project: "Histolochemical Analysis of Tissues and Organs Period of grant: July 1, 1946, to June 30, 1947. Panel on enzymes: Investigator: Barron, E. S. Guzman. Institution: University of Chicago. Title of project: "Study of Cell Division Under the Action of X-rays and Enzyme Studies in Fast Multiplying Cells." $3,500 6,000 5, 000 5, 500 20, 000 $15,000 List of research projects recommended to the American Cancer Society by the committee on growth-Continued DIVISION OF CHEMISTRY-continued Panel on enzymes-Continued Period of grant: July 1, 1946, to June 30, 1947. $5,000 Institution: New York University Medical College. Title of project: "The Isolation and Characterization of Tissue Period of grant: January 1, 1946, to June 30, 1947 22,500 Investigators: Graff, S., Ph. D.-Haagensen, C. D., M. D. Institution: Columbia University. Title of project: "Nucleic Acid of Normal and Cancer Tissue." Period of grant: January 1, 1946, to June 30, 1947 Investigators: Kamen, Martin D., Ph. D.-Spiegelmen, S., Ph. D. 6,000 Institution: Washington University, St. Louis. Title of project: "Mechanism of Synthesis and Maintenance of En- Period of grant: July 1, 1946, to June 30, 1947 6,000 Investigator: Mazia, Daniel, Ph. D. Institution: University of Missouri, Columbia. Title of project: "Enzyme Chemistry of Chromosomes." Period of grant: January 1, 1946, to June 30, 1947– 5,000 Investigator: Potter, Van R., Ph. D. Institution: University of Wisconsin. Title of project: "An Investigation of the Phosphorylated Metabolites of Tumor Cells Using the in situ Freezing Technique." Investigators: Hofman, Klaus, Ph. D.-Axelrod, A. E., Ph. D. Institution: University of Pittsburgh. Title of project: "Mechanism of Action of Some of the Newer Members of Vitamin B Complex." Period of grant: July 1, 1946, to June 30, 1947_ 6,300 Investigator: Rusch, Harold P., M. D. Institution: University of Wisconsin. Title of project: "Dietary Factors That Effect Tumor Formulations" (C. A. Baumann). "The Effect of Caloric Restriction on Cancer Formations" Title of project: "The Isolation and Characterization of Tissue Period of grant: July 1, 1946, to June 30, 1947_. Investigator: Chargaff, E., Ph. D. Institution: Columbia University. Title of project: "An Investigation of Lipoproteins." Period of grant: July 1, 1946, to June 30, 1947_. 4,500 7,000 List of research projects recommended to the American Cancer Society by the committee on growth-Continued DIVISION OF CHEMISTRY-continued Panel on proteins-Continued Investigator: Luck, J. Murray, Ph. D. Title of project: "The Fractionation of the Proteins of the Liver." Investigator: Rittenberg, D., Ph. D. Institution: Columbia University. Title of project: "Role of Metabolic Reactions in Proteins of Normal and Growing Tissues." $6,000 17,500 81, 700 Period of grant: July 1, 1946, to June 30, 1947 6, 000 Investigator: Wilson, D. Wright, Ph. D. Institution: University of Pennsylvania. Title of project: "Intermediary Metabolism of Proteins, Fats, and Period of grant: July 1, 1946, to June 30, 1947- 12, 400 Investigator: Wood, Harland G., Ph. D. Institution: University of Minnesota Medical School. Title of project: "Isotopic Tracer Studies of Biochemical Problems Title of project: "Development and Application of Physical Micro techniques to the Study of Cellular Growth." Period of grant: July 1, 1946, to June 30, 1947. 13, 200 Investigators: Loofbourrow, J. R., Sc. D.: Bear, R. S., Ph. D. Title of project: Development of Ultraviolet Microscopy as a Period of grant: July 1, 1946, to June 30, 1947_ 6, 500 Investigator: Williams, Robley C., Ph. D. Institution: University of Michigan. Title of project: "Electron Microscopic Study of the Physical Properties and Growth Phenomena of Protein Macromolecules." Period of grant: July 1, 1946, to June 30, 1947. 7,000 Investigators: Kamen, Martin D., Ph. D.-Spiegelman, S. Institution: Washington University, St. Louis. Title of project: "Mechanism of Synthesis and Maintenance of Period of grant: July 1, 1946, to June 30, 1947 5,000 Investigator: Nier, Alfred O., Ph. D. Institution: University of Minnesota. Title of project: "Development of Mass Spectrometer." List of research projects recommended to the American Cancer Society by the committee on growth-Continued DIVISION OF CLINICAL INVESTIGATIONS Panel on clinical investigation in endocrinology: Investigator: Means, J. H., M. D. Institution: Harvard University. Title of project: "A Study of Cancer of the Thyroid." GENERAL GRANTS Institution: National Academy of Sciences. For support of an existing central office (now under the jurisdiction of the Committee on Insect and Rodent Control) for the correlation of chemical structure with the biological activities of compounds, in order that the Committee on Growth may have free access to records already assembled and share in the costs of assembling additional biochemical data of particular interest in cancer research. Period of grant: Feb. 1, 1946, to July 1, 1946. For purchase of stable isotropic tracers, including carbon 13, nitrogen 15, sulfur 34, oxygen 18, and others as appear appropriate for the support of research of the grantees of The American Cancer Society. Period of grant: Mar. 1, 1946, to June 30, 1947_. Institution: University of Rochester School of Medicine. Institution: Washington University, St. Louis. Investigators: Kamen, Martin D.—Spiegelman, S. "Mechanism of Syn thesis and Maintenance of Enzymes in Cells." Period of grant: July 1, 1946, to June 30, 1947. Total____ Biology Chemistry.. Clinical investigation__. Physics General grants. Total $9,925 5,000 50,000 17,875 5,500 78,375 In addition to the above grants, 124 additional applications totaling $1,490,049 are now being considered by the committee, as well as 29 additional requests for 3-year research fellowships totaling $244,175. These requests, plus many others which leading institutions are known to be formulating, together with the continuation of grants already made, will call for at least an additional $3,000,000 from the funds which the American Cancer Society is seeking to raise this year. Since the publication of this report the following grants, recommended by the committee on growth, have been approved by the executive committee of the American Cancer Society: Investigators: Hummell, K. P., Ph. D.; Little, C. C., Sc. D. Title of project: "Quality and Quantity of the Mammary Tumor Inciter as Related to Tumor Incidence." Period of grant: July 1, 1946 to June 30, 1947_ Investigator: Russell, William L., Ph. D. Institution: Roscoe B. Jackson Memorial Laboratory. Title of project: "Prenatal Environment." $5, 200 Period of grant: July 1, 1946 to June 30, 1947_ Investigator: Snell, George D., Sc. D. Institution: Roscoe B. Jackson Memorial Laboratory. Title of project: "A Study of the Induction of Somatic and Germinal Period of grant: January 1, 1946, to June 30, 1947– 5, 600 5, 250 LIST OF APPROVED FELLOWSHIPS RECOMMENDED TO THE EXECUTIVE COMMITTEE OF THE AMERICAN CANCER SOCIETY BY THE COMMITTED ON GROWTH AS OF MARCH 25, 1946 1. Senior fellowships (1) Fellow: Saul Malkiel, A. B., M. A., Ph. D., M. D. Home address: 43 Strathmore Road, Brookline, Mass. Institution: The Rockefeller Institute for Medical Research, Princeton, N. J. Period of fellowship: October 1, 1946, to September 30, 1949. Association with: Dr. W. M. Stanley. (2) Fellow: Robert Nieset, A. B., B. S. ed., M. A., Ph. D. Home address: 2375 Jeanne Street, Pittsfield Village, Ann Arbor, Mich. Period of fellowship: April 1, 1946, to March 31, 1949. II. Fellowships (3) Fellow: Robert Montgomery Bird, B. S., M. D. (4) Fellow: Joseph H. Burchenal, M. D. Home address: 210 South Walnut Street, Milford, Del. Period of fellowship: March 8, 1946, to June 30, 1947. (5) Fellow: Ivan DeRay Frantz, Jr., A. B., M. D. Home address: 119 Vermont Avenue, Clarksburg, W. Va. Period of fellowship: February 1, 1946, to June 30, 1947. III. Predoctoral fellowships (6) Fellow: Clarence Morley Connelly, A. B. Home address: Care of L. H. Connelly, R. D. 3, Ithaca, N. Y. Institution: Johnson Research Foundation, University of Pennsylvania. Under direction of: Dr. Detlev W. Bronk. |