Alcohol and the Gastrointestinal TractManfred V. Singer, David Brenner Karger Medical and Scientific Publishers, 2006 - 262 pages Alcohol-related disorders account for an enormous part of the global mortality and morbidity, with most patients being treated in gastroenterology. For this book, a team of internationally renowned experts has contributed state-of-the-art reviews on alcohol-related epidemiology, diseases of the gastrointestinal tract, liver and pancreas as well as the question of how to guide alcoholics psychologically. The first paper evaluates epidemiological data on the impact of alcohol consumption on total morbidity and mortality. This is followed by a critical appraisal of the effect of moderate drinking on the risk and pathophysiological mechanisms of gastrointestinal diseases and of certain health benefits of moderate alcohol consumption. An assessment of available animal models to explain the latest findings in basic alcohol research is followed by a discussion of the effects of alcohol on the various parts of the gastrointestinal system, with special emphasis on the pancreas and liver. Reviews of the well-known association between alcohol consumption and increased risk of cancer and a discussion on how best to care for alcoholics in view of the presented research advances conclude this volume. For those interested in alcohol-related epidemiology, molecular mechanisms, pathophysiology, clinical aspects and the treatment of alcohol-induced diseases of the gastrointestinal tract, liver and pancreas, this publication contains a wealth of information. |
Contents
Current Needs and Methodological Challenges | 1 |
Moderate Alcohol Consumption and the Gastrointestinal Tract | 15 |
A Review of Pathophysiological Processes | 27 |
Animal Models and Their Results in Gastrointestinal Alcohol Research | 35 |
AlcoholRelated Diseases of the Mouth and Throat | 59 |
AlcoholRelated Diseases of the Esophagus and Stomach | 74 |
Effect of Alcohol Consumption on the Gut | 91 |
Alcoholic Pancreatitis | 105 |
Genetic Polymorphisms in Alcoholic Pancreatitis | 148 |
Clinical Syndromes of Alcoholic Liver Disease | 161 |
Molecular Mechanisms of AlcoholInduced Hepatic Fibrosis | 177 |
Treatment of Alcoholic Liver Disease | 196 |
Alcohol and Hepatitis C | 214 |
Alcohol Consumption and Cancer of the Gastrointestinal Tract | 234 |
Guidelines for Practitioners | 246 |
256 | |
Molecular Mechanisms of Alcoholic Pancreatitis | 122 |
Treatment of Alcoholic Pancreatitis | 139 |
Other editions - View all
Alcohol and the Gastrointestinal Tract: Reprint Of: Digestive Diseases 2005 ... M.V. Singer,D.A. Brenner No preview available - 2006 |
Common terms and phrases
abstinence acetaldehyde acinar cells acute and chronic acute ethanol acute pancreatitis alco alcohol abuse Alcohol Clin Exp alcohol intake alcohol-related alcoholic beverages alcoholic chronic pancreatitis alcoholic cirrhosis alcoholic hepatitis alcoholic liver disease alcoholic pancreatitis animal models antibody associated Brenner carcinogenesis carcinogenic chronic alcohol consumption chronic pancreatitis Clin Exp Res clinical collagen colon cytokines damage decreased dehydrogenase drinkers drinking effects of alcohol effects of ethanol enzymes esophageal esophageal cancer ethanol-induced exocrine fibrogenesis g/day Gastroenterol Gastroenterology gastrointestinal tract gene genetic hepatic stellate cells hepatocytes Hepatol Hepatology histological holic human increased induced infection inhibition inhibitor Kupffer cells lipid liver fibrosis liver injury mechanisms metabolites mortality mucosa mutations neck cancer necrosis oral oxidative stress patients with alcoholic patients with chronic Pirola RC polymorphisms protein risk factor role Seitz HK Singer MV steatosis studies therapy tion tissue treatment vitamin vitro Whitcomb DC